Continuous performance of a novel motor sequence leads to highly correlated striatal and hippocampal perfusion increases
The time course of changes in regional cerebral perfusion during a continuous motor learning task performed with the right hand was monitored using the arterial spin labeling (ASL) technique at high field (3 T). ASL allowed measuring explicit learning related effects in neural activity elicited th...
| Main Authors: | , , , , |
|---|---|
| Format: | info:eu-repo/semantics/article |
| Language: | eng |
| Published: |
Elsevier
2010
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10171/13046 |
| _version_ | 1793400029058170880 |
|---|---|
| author | Fernández-Seara, M.A. (María A.) Aznárez-Sanado, M. (Maite) Mengual, E. (Elisa) Loayza, F.R. (Francis R.) Pastor, M.A. (María A.) |
| author_facet | Fernández-Seara, M.A. (María A.) Aznárez-Sanado, M. (Maite) Mengual, E. (Elisa) Loayza, F.R. (Francis R.) Pastor, M.A. (María A.) |
| author_sort | Fernández-Seara, M.A. (María A.) |
| collection | DSpace |
| description | The time course of changes in regional cerebral perfusion during a continuous motor learning task performed
with the right hand was monitored using the arterial spin labeling (ASL) technique at high field (3 T). ASL
allowed measuring explicit learning related effects in neural activity elicited throughout a 6 minute task
period. During this time learning took place as demonstrated by performance improvement. Comparing the
initial and final learning phases, perfusion decreases were detected in most of the cortical regions recruited
during early learning. More interestingly however perfusion increases were observed in a few cortical and
subcortical regions of the contralateral hemisphere: the supplementary motor area, the primary somatosensory
area, the posterior insula and posterior putamen, the hippocampus and bilaterally the retrosplenial
cortex. Moreover, perfusion increases in the posterior putamen and hippocampus were highly correlated
during the learning period. These results support the hypothesis that the striatum and hippocampus form
interactive memory systems with parallel processing |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-13046 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2010 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-130462021-05-31T09:49:42Z Continuous performance of a novel motor sequence leads to highly correlated striatal and hippocampal perfusion increases Fernández-Seara, M.A. (María A.) Aznárez-Sanado, M. (Maite) Mengual, E. (Elisa) Loayza, F.R. (Francis R.) Pastor, M.A. (María A.) Arterial spin labeling 3D GRASE Motor sequence learning Procedural memory Putamen Hippocampus The time course of changes in regional cerebral perfusion during a continuous motor learning task performed with the right hand was monitored using the arterial spin labeling (ASL) technique at high field (3 T). ASL allowed measuring explicit learning related effects in neural activity elicited throughout a 6 minute task period. During this time learning took place as demonstrated by performance improvement. Comparing the initial and final learning phases, perfusion decreases were detected in most of the cortical regions recruited during early learning. More interestingly however perfusion increases were observed in a few cortical and subcortical regions of the contralateral hemisphere: the supplementary motor area, the primary somatosensory area, the posterior insula and posterior putamen, the hippocampus and bilaterally the retrosplenial cortex. Moreover, perfusion increases in the posterior putamen and hippocampus were highly correlated during the learning period. These results support the hypothesis that the striatum and hippocampus form interactive memory systems with parallel processing 2010-09-27T14:46:16Z 2010-09-27T14:46:16Z 2009-05-15 info:eu-repo/semantics/article https://hdl.handle.net/10171/13046 eng info:eu-repo/semantics/closedAccess Elsevier |
| spellingShingle | Arterial spin labeling 3D GRASE Motor sequence learning Procedural memory Putamen Hippocampus Fernández-Seara, M.A. (María A.) Aznárez-Sanado, M. (Maite) Mengual, E. (Elisa) Loayza, F.R. (Francis R.) Pastor, M.A. (María A.) Continuous performance of a novel motor sequence leads to highly correlated striatal and hippocampal perfusion increases |
| title | Continuous performance of a novel motor sequence leads to highly correlated striatal and hippocampal perfusion increases |
| title_full | Continuous performance of a novel motor sequence leads to highly correlated striatal and hippocampal perfusion increases |
| title_fullStr | Continuous performance of a novel motor sequence leads to highly correlated striatal and hippocampal perfusion increases |
| title_full_unstemmed | Continuous performance of a novel motor sequence leads to highly correlated striatal and hippocampal perfusion increases |
| title_short | Continuous performance of a novel motor sequence leads to highly correlated striatal and hippocampal perfusion increases |
| title_sort | continuous performance of a novel motor sequence leads to highly correlated striatal and hippocampal perfusion increases |
| topic | Arterial spin labeling 3D GRASE Motor sequence learning Procedural memory Putamen Hippocampus |
| url | https://hdl.handle.net/10171/13046 |
| work_keys_str_mv | AT fernandezsearamamariaa continuousperformanceofanovelmotorsequenceleadstohighlycorrelatedstriatalandhippocampalperfusionincreases AT aznarezsanadommaite continuousperformanceofanovelmotorsequenceleadstohighlycorrelatedstriatalandhippocampalperfusionincreases AT mengualeelisa continuousperformanceofanovelmotorsequenceleadstohighlycorrelatedstriatalandhippocampalperfusionincreases AT loayzafrfrancisr continuousperformanceofanovelmotorsequenceleadstohighlycorrelatedstriatalandhippocampalperfusionincreases AT pastormamariaa continuousperformanceofanovelmotorsequenceleadstohighlycorrelatedstriatalandhippocampalperfusionincreases |