Early Changes in Hippocampal Eph Receptors Precede the Onset of Memory Decline in Mouse Models of Alzheimer’s Disease

Early Changes in Hippocampal Eph Receptors Precede the Onset of Memory Decline in Mouse Models of Alzheimer’s Disease

Abstract. Synapse loss occurs early in Alzheimer’s disease (AD) and is considered the best pathological correlate of cognitive decline. Ephrins and Eph receptors are involved in regulation of excitatory neurotransmission and play a role in cytoskeleton remodeling. We asked whether alterations in E...

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Bibliographic Details
Main Authors: Simon, A.M. (Ana María), Raquel, Ricobaraza, A. (Ana), Escribano, L. (Luis), Schiapparelli, L. (Lucio), Cuadrado-Tejedor, M. (Mar), Perez-Mediavilla, L.A. (Luis Alberto), Avila, J. (Jesús), Rio, J. (Joaquín) del, Frechilla, D. (Diana)
Format: info:eu-repo/semantics/article
Language:eng
Published: IOS Press 2010
Subjects:
Alzheimer's disease
Cofilin
Ephrin
Eph receptor
Glutamate receptor
LIM-kinase
Memory
P21-activated kinase
Online Access:https://hdl.handle.net/10171/13229

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