Co-encapsulation of an antigen and CpG oligonucleotides into PLGA microparticles by TROMS technology.
It seems well established that CpG oligonucleotides Th1 biased adjuvant activity can be improved when closely associated with a variety of antigens in, for example, microparticles. In this context, we prepared 1-μm near non-charged PLGA 502 or PLGA 756 microparticles that loaded with high efficie...
| Main Authors: | , , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
| Published: |
Elsevier
2011
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10171/17366 |