Co-encapsulation of an antigen and CpG oligonucleotides into PLGA microparticles by TROMS technology.

It seems well established that CpG oligonucleotides Th1 biased adjuvant activity can be improved when closely associated with a variety of antigens in, for example, microparticles. In this context, we prepared 1-μm near non-charged PLGA 502 or PLGA 756 microparticles that loaded with high efficie...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: San-Roman, B. (Beatriz), Irache, J.M. (Juan Manuel), Gomez, S. (Sara), Tsapis, N. (Nicolás), Gamazo, C. (Carlos), Espuelas, S. (Socorro)
Format: info:eu-repo/semantics/article
Sprache:eng
Veröffentlicht: Elsevier 2011
Schlagworte:
Online Zugang:https://hdl.handle.net/10171/17366