Synthesis and biological evaluation of new quinoxaline derivatives as antioxidant and anti-inflammatory agents

Synthesis and biological evaluation of new quinoxaline derivatives as antioxidant and anti-inflammatory agents

We report the synthesis, anti-inflammatory and antioxidant activities of novel quinoxaline and quinoxaline 1,4-di-N-oxide derivatives. Microwave assisted methods have been used in order to optimize reaction times and to improve the yields. The tested compounds presented important scavenging activiti...

Bibliografiset tiedot
Päätekijät:	Burguete, A. (Asunción), Pontiki, E. (Eleni), Hadjipavlou-Litina, D. (Dimitra), Ancizu, S. (Saioa), Raquel, Solano, B. (Beatriz), Moreno-de-Viguri, E. (Elsa), Torres, E. (Enrique), Pérez-Silanes, S. (Silvia), Aldana, I. (Ignacio), Monge, A. (Antonio)
Aineistotyyppi:	info:eu-repo/semantics/article
Kieli:	eng
Julkaistu:	Wiley-Blackwell 2011
Aiheet:	Quinoxaline derivatives Anti-inflammatory agents 1,4-di-N-oxide derivatives Soybean lipoxygenase
Linkit:	https://hdl.handle.net/10171/18591

Samankaltaisia teoksia

New 1,4-di-N-oxide-quinoxaline-2-ylmethylene isonicotinic acid hydrazide derivatives as anti-Mycobacterieum tuberculosis agents
Tekijä: Torres, E. (Enrique), et al.
Julkaistu: (2011)

Quinoxaline 1,4-di-N-oxide and the Potential for Treating Tuberculosis
Tekijä: Vicente, E. (Esther), et al.
Julkaistu: (2011)

Synthesis, biological evaluation and structure-activity relationships of new quinoxaline derivatives as anti-Plasmodium falciparum agents
Tekijä: Aldana, I. (Ignacio), et al.
Julkaistu: (2014)

New amide derivatives of quinoxaline 1,4-di-N-oxide with leishmanicidal and antiplasmodial activities
Tekijä: Barea, C. (Carlos), et al.
Julkaistu: (2013)

Cyclic voltammetric study of some anti-Chagas-active 1,4-dioxidoquinoxalin-2-yl ketone derivatives
Tekijä: Crawford, P.W. (Philip W.), et al.
Julkaistu: (2014)

Novel quinoxaline 1,4-di-N-oxide derivatives as new potential antichagasic agents
Tekijä: Pérez-Silanes, S. (Silvia), et al.
Julkaistu: (2014)

New 3-methylquinoxaline-2-carboxamide 1,4-di-N-oxide derivatives as anti- Mycobacterium tuberculosis agents.
Tekijä: Monge, A. (Antonio), et al.
Julkaistu: (2014)

Synthesis and antimycobacterial activity of new quinoxaline-2- carboxamide 1,4-di-N-oxide derivatives.
Tekijä: Monge, A. (Antonio), et al.
Julkaistu: (2014)

Substitutions of fluorine atoms and phenoxy groups in the synthesis of quinoxaline 1,4-di-N-oxide derivatives.
Tekijä: Vicente, E. (Esther), et al.
Julkaistu: (2012)

Primaquine–quinoxaline 1,4‑di‑N‑oxide hybrids with action on the exo‑erythrocytic forms of Plasmodium induce their efect by the production of reactive oxygen species
Tekijä: Bonilla‑Ramírez, L. (Leonardo), et al.
Julkaistu: (2022)

Synthesis and Preclinical Development of novel Organoselenium compounds as Multi-Target and Bioactive Agents
Tekijä: Astráin-Redín, N. (Nora), et al.
Julkaistu: (2023)

New salicylamide and sulfonamide derivatives of quinoxaline 1,4-di-N-oxide with antileishmanial and antimalarial activities
Tekijä: Barea, C. (Carlos), et al.
Julkaistu: (2012)

Synthesis and antiplasmodial activity of 3-furyl and 3-thienylquinoxaline-2-carbonitrile 1,4-di-N-oxide derivatives
Tekijä: Vicente, E. (Esther), et al.
Julkaistu: (2012)

An Efficient One-Pot Protocol for the Synthesis of Substituted 3,4-Dihydropyrimidin-2(1H)-ones Using Metallophthalocyanines (MPcs) as Potent Heterogeneous Catalysts: Synthesis, Characterization, Aggregation and Antimicrobial Activity
Tekijä: Hamdi, Naceur, et al.
Julkaistu: (2020)

Design and synthesis of new selenoderivatives with biomedical applications
Tekijä: Ramos-Inza, S. (Sandra), et al.
Julkaistu: (2023)

Efficacy of quinoxaline-2-carboxylate 1,4-di-N-oxide derivatives in experimental tuberculosis
Tekijä: Vicente, E. (Esther), et al.
Julkaistu: (2013)

Synthesis and biological evaluation of quinoxaline di-N-oxide derivatives with in vitro trypanocidal activity
Tekijä: Pérez-Silanes, S. (Silvia), et al.
Julkaistu: (2016)

An Extension of the Concept of Derivative: Its Application to Intertemporal Choice
Tekijä: Cruz Rambaud, Salvador, et al.
Julkaistu: (2020)

Design and synthesis of novel quinoxaline derivatives as potential candidates for treatment of multidrug-resistant and latent tuberculosis
Tekijä: Santivañez-Veliz, M. (Mery), et al.
Julkaistu: (2016)

Asymptotics of the L2 norm of derivatives of OPUC
Tekijä: Martínez-Finkelshtein, Andrei, et al.
Julkaistu: (2012)

Unexpected reduction of ethyl 3-phenylquinoxaline-2- carboxylate 1,4-di-N-oxide derivatives by amines.
Tekijä: Lima, L.M. (Lidia M.), et al.
Julkaistu: (2012)

Aplicación de software matemático DERIVE, para el logro de aprendizajes en aplicaciones del cálculo diferencial e integral, en estudiantes universitarios
Tekijä: Muñoz Suárez, Manuel Antonio
Julkaistu: (2018)

Evaluation of the Antiproliferative Properties of CpRu Complexes Containing N-Methylated Triazaphosphaadamantane Derivatives.
Tekijä: Alguacil Alarcón, Andrés, et al.
Julkaistu: (2024)

Dietary inflammatory index and incidence of cardiovascular disease in the SUN cohort
Tekijä: Ramallal, R. (Raul), et al.
Julkaistu: (2015)

Análisis experimental de las condiciones que influyen en la aparición del comportamiento humorístico
Tekijä: Bebber, Matheus
Julkaistu: (2022)

Synthesis of quinoxaline 1,4-di-N-oxide derivatives on solid support using room temperature and microwave-assisted solvent-free procedures
Tekijä: Gomez-Caro, L.C. (Lilia C.), et al.
Julkaistu: (2013)

The outer membranes of Brucella spp. are not barriers to hydrophobic permeants
Tekijä: Martinez-de-Tejada, G. (Guillermo), et al.
Julkaistu: (2013)

Studies on log Po/w of quinoxaline di-N-oxides: a comparison of RP-HPLC experimental and predictive approaches.
Tekijä: Moreno-de-Viguri, E. (Elsa), et al.
Julkaistu: (2012)

New 1-aryl-3-substituted propanol derivatives as antimalarial agents
Tekijä: Pérez-Silanes, S. (Silvia), et al.
Julkaistu: (2012)

Dietary tryptophan depletion alters the faecal bacterial community structure of compulsive drinker rats in schedule-induced polydipsia
Tekijä: Merchán Carrillo, Ana María, et al.
Julkaistu: (2024)

Problemas de cálculo diferencial: cuestiones, ejercicios y tratamiento en DERIVE

New quinoxaline 1,4-di-N-oxide derivatives: Trypanosomaticidal activities and enzyme docking simulation
Tekijä: Estevez, Y. (Yannick), et al.
Julkaistu: (2014)

Designing Single-Molecule Magnets as Drugs with Dual Anti-Inflammatory and Anti-Diabetic Effects
Tekijä: Navas, Arturo, et al.
Julkaistu: (2020)

Oxidative stress is associated with an increased antioxidant defense in elderly subjects: a multilevel approach
Tekijä: Flores-Mateo, G. (Gemma), et al.
Julkaistu: (2014)

Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population
Tekijä: Marti-del-Moral, A. (Amelia), et al.
Julkaistu: (2014)

New quinoxaline and indole derivatives as MT1 and MT2 receptor agonists
Tekijä: Ancizu, S. (Saioa), et al.
Julkaistu: (2014)

Dietary inflammatory index and incidence of cardiovascular disease in the PREDIMED study
Tekijä: PREDIMED, et al.
Julkaistu: (2015)

Partially halogenated chlorofluorocarbon: ethane derivativesChlorofluorocarbons, partially halogenated: ethane derivatives)

Anti-leishmanial and structure-activity relationship of ring substituted 3-phenyl-1-(1,4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one derivatives
Tekijä: Burguete, A. (Asunción), et al.
Julkaistu: (2015)

Synthesis and Biological Evaluation of Cassane Diterpene (5α)-Vuacapane-8(14), 9(11)-Diene and of Some Related Compounds
Tekijä: Zentar, Houda, et al.
Julkaistu: (2022)