Poly(D,L-lactide-coglycolide) particles containing gentamicin: pharmacokinetics and pharmacodynamics in Brucella melitensis-infected mice

Drug delivery systems containing gentamicin were studied as a treatment against experimental brucellosis in mice. Micro- and nanoparticles prepared by using poly(D,L-lactide-coglycolide) (PLGA) 502H and microparticles made of PLGA 75:25H were successfully delivered to the liver and the spleen, the t...

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Main Authors: Lecaroz, M.C. (María Concepción), Blanco-Prieto, M.J. (María José), Campanero, M.A. (Miguel Angel), Salman, H.H. (Hesham H.), Gamazo, C. (Carlos)
Format: info:eu-repo/semantics/article
Language:eng
Published: American Society for Microbiology 2011
Subjects:
Online Access:https://hdl.handle.net/10171/19114