Randomized crossover pharmacokinetic evaluation of subcutaneous versus intravenous granisetron in cancer patients treated with platinum-based chemotherapy

Randomized crossover pharmacokinetic evaluation of subcutaneous versus intravenous granisetron in cancer patients treated with platinum-based chemotherapy

BACKGROUND: 5-HT3-receptor antagonists are one of the mainstays of antiemetic treatment, and they are administered either i.v. or orally. Nevertheless, sometimes neither administration route is feasible, such as in patients unable to admit oral intake managed in an outpatient setting. Our objecti...

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Main Authors: Gurpide, A. (Alfonso), Sadaba, B. (Belén), Martin-Algarra, S. (Salvador), Azanza, J.R. (José Ramón), Lopez-Picazo, J.M. (José M.), Campanero, M.A. (Miguel Angel), Cabello, J.P. (J.P.), Gil-Aldea, I. (I.), Cruz, S. (S.) de la, Fernandez-Gallego, V. (V.), Reyna, C. (Carmen), Olier, C. (Clara), Blanco-Prieto, M.J. (María José), Ceballos-Viro, J. (Jaime), Garcia-Foncillas, J. (Jesús), Perez-Gracia, J.L. (Jose Luis)
Format: info:eu-repo/semantics/article
Language:eng
Published: AlphaMed Press 2011
Subjects:
Emesis
Granisetron
Pharmacokinetics
Subcutaneous
Online Access:https://hdl.handle.net/10171/19115

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