The c.-1639G > A polymorphism of the VKORC1 gene is a major determinant of the response to acenocoumarol in anticoagulated patients

The c.-1639G > A polymorphism of the VKORC1 gene is a major determinant of the response to acenocoumarol in anticoagulated patients

Much of the variability in the sensitivity to warfarin in anticoagulated patients is associated with the c.-1639G > A polymorphism of the vitamin K-epoxide reductase (VKORC1) gene. However, its association with the acenocoumarol dose in patients under anticoagulant therapy has not been studied. T...

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Bibliographic Details
Main Authors: Montes, R. (Ramón), Ruiz-de-Gaona, E. (Estefanía), Martinez-Gonzalez, M.A. (Miguel Ángel), Alberca, I. (Ignacio), Hermida, J. (José)
Format: info:eu-repo/semantics/article
Language:eng
Published: Blackwell Publishing 2012
Subjects:
Vitamin K
Drugs
Anticoagulation
Online Access:https://hdl.handle.net/10171/21989

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