| Summary: | To analyse the assessment reports published on the GENESIS webpage
(Group for Innovation, Assessment, Standardisation and Research in the Selection
of Drugs) and assess the variability of the group's proposals to include drugs in
the Formulary. METHOD: We analysed reports published by hospitals on the GENESIS
webpage between 2004 and 2007. Data were collected on drugs and indications, ATC
group, open or restricted access publications, hospital, and publication date. We
drafted a questionnaire that would measure to what extent to what extent the
9-section model recommended by GENESIS was included in each report. For drugs
with two or more reports, we analysed whether the recommendation coincided and
the possible cause in the event of conflict. RESULTS: We analysed 416 reports
corresponding to 185 different drug indications. 93% included 6 or more of the
recommended sections, a number which increased over time. The most frequently
included sections were: approved indications (92%), mechanism of action (95%),
and references (86%) (percentages from 2007). Sections which had an increasing
but lower percentage were: differential characteristics (60%), literature search
method (40%) and conclusions with a summary of efficacy, safety and cost data
(52%). 73% of which had definite recommendations, which coincided for 42 out of
the 67 drugs with more than one recommendation report. CONCLUSIONS: The work
carried out by the GENESIS group has enabled Spanish hospitals to share their
drug assessment reports and making them more complete, although there are still
some aspects that can be improved.
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