Assessment of cyst content using mean gray value for discriminating endometrioma from other unilocular cysts in premenopausal women
Objective To assess whether the analysis of cyst content using mean gray value (MGV) can discriminate ovarian endometriomas from other unilocular ovarian cysts in premenopausal women. Methods Stored three-dimensional (3D) volumes from 54 unilocular ovarian cysts diagnosed in 50 premenopausal w...
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
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Wiley-Blackwell
2012
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| Online Access: | https://hdl.handle.net/10171/22528 |
| _version_ | 1793399923031408640 |
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| author | Alcazar, J.L. (Juan Luis) Leon, M. (M.) Galván, L. (Luis) Guerriero, S. (Stefano) |
| author_facet | Alcazar, J.L. (Juan Luis) Leon, M. (M.) Galván, L. (Luis) Guerriero, S. (Stefano) |
| author_sort | Alcazar, J.L. (Juan Luis) |
| collection | DSpace |
| description | Objective To assess whether the analysis of cyst content
using mean gray value (MGV) can discriminate ovarian
endometriomas from other unilocular ovarian cysts in
premenopausal women.
Methods Stored three-dimensional (3D) volumes from 54
unilocular ovarian cysts diagnosed in 50 premenopausal
women (mean age, 37 (range, 22–50) years) were
analyzed to calculate the MGV from cyst content. Cysts
with solid components or septations were excluded.
MGV was calculated in all cases with the Virtual
Organ Computer-aided AnaLysisTM technique. The Bmode
presumptive diagnosis based on the examiner’s
subjective impression was also recorded.
Results Sixteen of the cysts resolved spontaneously and
were given a final clinical diagnosis of hemorrhagic
functional cyst, while 38 cysts were removed surgically
(diagnosed histologically as seven simple cysts, three
hemorrhagic cysts, 20 endometriomas, five mucinous
cysts and three paraovarian cysts). B-mode diagnoses
were as follows: seven simple cysts, 18 hemorrhagic
cysts, 24 endometriomas, three mucinous cysts and two
paraovarian cysts. MGV was significantly higher in
ovarian endometrioma when compared with all other
kinds of cyst. The receiver–operating characteristics
curve showed that using an MGV cut-off ≥15.560
had a sensitivity of 85% and a specificity of 76.5%
for diagnosing ovarian endometrioma (area under the
curve, 0.831; 95% CI, 0.718–0.944). These figures were
similar to those for B-mode diagnosis (sensitivity, 90%;
specificity, 82%) (McNemar test, P = 1.000). Combining
B-mode and MGV gave a sensitivity of 80% and a
specificity of 91%.
Conclusion Cyst content MGV is higher in ovarian
endometrioma than it is in other unilocular ovarian cysts.
The diagnostic performance of MGV is similar to that of
the examiner’s subjective impression. The combination of
both criteria achieves the highest specificity |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-22528 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2012 |
| publisher | Wiley-Blackwell |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-225282023-05-22T07:50:16Z Assessment of cyst content using mean gray value for discriminating endometrioma from other unilocular cysts in premenopausal women Alcazar, J.L. (Juan Luis) Leon, M. (M.) Galván, L. (Luis) Guerriero, S. (Stefano) Endometrioma Diagnosis Ultrasound Objective To assess whether the analysis of cyst content using mean gray value (MGV) can discriminate ovarian endometriomas from other unilocular ovarian cysts in premenopausal women. Methods Stored three-dimensional (3D) volumes from 54 unilocular ovarian cysts diagnosed in 50 premenopausal women (mean age, 37 (range, 22–50) years) were analyzed to calculate the MGV from cyst content. Cysts with solid components or septations were excluded. MGV was calculated in all cases with the Virtual Organ Computer-aided AnaLysisTM technique. The Bmode presumptive diagnosis based on the examiner’s subjective impression was also recorded. Results Sixteen of the cysts resolved spontaneously and were given a final clinical diagnosis of hemorrhagic functional cyst, while 38 cysts were removed surgically (diagnosed histologically as seven simple cysts, three hemorrhagic cysts, 20 endometriomas, five mucinous cysts and three paraovarian cysts). B-mode diagnoses were as follows: seven simple cysts, 18 hemorrhagic cysts, 24 endometriomas, three mucinous cysts and two paraovarian cysts. MGV was significantly higher in ovarian endometrioma when compared with all other kinds of cyst. The receiver–operating characteristics curve showed that using an MGV cut-off ≥15.560 had a sensitivity of 85% and a specificity of 76.5% for diagnosing ovarian endometrioma (area under the curve, 0.831; 95% CI, 0.718–0.944). These figures were similar to those for B-mode diagnosis (sensitivity, 90%; specificity, 82%) (McNemar test, P = 1.000). Combining B-mode and MGV gave a sensitivity of 80% and a specificity of 91%. Conclusion Cyst content MGV is higher in ovarian endometrioma than it is in other unilocular ovarian cysts. The diagnostic performance of MGV is similar to that of the examiner’s subjective impression. The combination of both criteria achieves the highest specificity 2012-06-09T16:23:19Z 2012-06-09T16:23:19Z 2010 info:eu-repo/semantics/article https://hdl.handle.net/10171/22528 eng http://onlinelibrary.wiley.com/doi/10.1002/uog.7535/pdf info:eu-repo/semantics/openAccess application/pdf Wiley-Blackwell |
| spellingShingle | Endometrioma Diagnosis Ultrasound Alcazar, J.L. (Juan Luis) Leon, M. (M.) Galván, L. (Luis) Guerriero, S. (Stefano) Assessment of cyst content using mean gray value for discriminating endometrioma from other unilocular cysts in premenopausal women |
| title | Assessment of cyst content using mean gray value for discriminating endometrioma from other unilocular cysts in premenopausal women |
| title_full | Assessment of cyst content using mean gray value for discriminating endometrioma from other unilocular cysts in premenopausal women |
| title_fullStr | Assessment of cyst content using mean gray value for discriminating endometrioma from other unilocular cysts in premenopausal women |
| title_full_unstemmed | Assessment of cyst content using mean gray value for discriminating endometrioma from other unilocular cysts in premenopausal women |
| title_short | Assessment of cyst content using mean gray value for discriminating endometrioma from other unilocular cysts in premenopausal women |
| title_sort | assessment of cyst content using mean gray value for discriminating endometrioma from other unilocular cysts in premenopausal women |
| topic | Endometrioma Diagnosis Ultrasound |
| url | https://hdl.handle.net/10171/22528 |
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