Monitorización y efectos secundarios de los inmunosupresores en el trasplante
ABSTRACT The success of organ transplants and their consideration as a clearly established treatment in some indications is due to the development of immunosuppressant drugs. While it was not the first of the drugs to be employed, the introduction of cyclosporin in the 1980s in immunosuppressa...
Main Author: | |
---|---|
Format: | info:eu-repo/semantics/article |
Language: | spa |
Published: |
Gobierno de Navarra. Departamento de Salud
2012
|
Subjects: | |
Online Access: | https://hdl.handle.net/10171/22594 |
_version_ | 1793400198373834752 |
---|---|
author | Sadaba, B. (Belén) |
author_facet | Sadaba, B. (Belén) |
author_sort | Sadaba, B. (Belén) |
collection | DSpace |
description | ABSTRACT
The success of organ transplants and their consideration
as a clearly established treatment in some
indications is due to the development of immunosuppressant
drugs. While it was not the first of the drugs
to be employed, the introduction of cyclosporin in the
1980s in immunosuppressant treatment made possible
an increase in the number of transplants and the
success of this practice. From then onwards, immunosuppression
has been based on the use of a combination
of drugs, initially cyclosporin, corticoids and azathioprine.
In recent years new drugs have been
introduced that have opened up the possibilities of
treatment. But many pending questions remain, due
to the toxicity associated with their use and the possibility
of interaction with other drugs, which complicates
their use and can compromise the prognoses of
these patients.
Calcineurin inhibitors and mTOR are the drugs
involved with greater frequency in interactions with
other drugs, which makes it necessary to anticipate
this possibility |
format | info:eu-repo/semantics/article |
id | oai:dadun.unav.edu:10171-22594 |
institution | Universidad de Navarra |
language | spa |
publishDate | 2012 |
publisher | Gobierno de Navarra. Departamento de Salud |
record_format | dspace |
spelling | oai:dadun.unav.edu:10171-225942020-03-03T20:15:41Z Monitorización y efectos secundarios de los inmunosupresores en el trasplante Sadaba, B. (Belén) Immunosuppressants Medication interactions ABSTRACT The success of organ transplants and their consideration as a clearly established treatment in some indications is due to the development of immunosuppressant drugs. While it was not the first of the drugs to be employed, the introduction of cyclosporin in the 1980s in immunosuppressant treatment made possible an increase in the number of transplants and the success of this practice. From then onwards, immunosuppression has been based on the use of a combination of drugs, initially cyclosporin, corticoids and azathioprine. In recent years new drugs have been introduced that have opened up the possibilities of treatment. But many pending questions remain, due to the toxicity associated with their use and the possibility of interaction with other drugs, which complicates their use and can compromise the prognoses of these patients. Calcineurin inhibitors and mTOR are the drugs involved with greater frequency in interactions with other drugs, which makes it necessary to anticipate this possibility 2012-06-17T18:40:31Z 2012-06-17T18:40:31Z 2006 info:eu-repo/semantics/article https://hdl.handle.net/10171/22594 spa http://www.cfnavarra.es/salud/anales/textos/vol29/sup2/suple17.html info:eu-repo/semantics/openAccess application/pdf Gobierno de Navarra. Departamento de Salud |
spellingShingle | Immunosuppressants Medication interactions Sadaba, B. (Belén) Monitorización y efectos secundarios de los inmunosupresores en el trasplante |
title | Monitorización y efectos secundarios de los inmunosupresores en el trasplante |
title_full | Monitorización y efectos secundarios de los inmunosupresores en el trasplante |
title_fullStr | Monitorización y efectos secundarios de los inmunosupresores en el trasplante |
title_full_unstemmed | Monitorización y efectos secundarios de los inmunosupresores en el trasplante |
title_short | Monitorización y efectos secundarios de los inmunosupresores en el trasplante |
title_sort | monitorización y efectos secundarios de los inmunosupresores en el trasplante |
topic | Immunosuppressants Medication interactions |
url | https://hdl.handle.net/10171/22594 |
work_keys_str_mv | AT sadababbelen monitorizacionyefectossecundariosdelosinmunosupresoreseneltrasplante |