Monitorización y efectos secundarios de los inmunosupresores en el trasplante

ABSTRACT The success of organ transplants and their consideration as a clearly established treatment in some indications is due to the development of immunosuppressant drugs. While it was not the first of the drugs to be employed, the introduction of cyclosporin in the 1980s in immunosuppressa...

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Main Author: Sadaba, B. (Belén)
Format: info:eu-repo/semantics/article
Language:spa
Published: Gobierno de Navarra. Departamento de Salud 2012
Subjects:
Online Access:https://hdl.handle.net/10171/22594
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author Sadaba, B. (Belén)
author_facet Sadaba, B. (Belén)
author_sort Sadaba, B. (Belén)
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description ABSTRACT The success of organ transplants and their consideration as a clearly established treatment in some indications is due to the development of immunosuppressant drugs. While it was not the first of the drugs to be employed, the introduction of cyclosporin in the 1980s in immunosuppressant treatment made possible an increase in the number of transplants and the success of this practice. From then onwards, immunosuppression has been based on the use of a combination of drugs, initially cyclosporin, corticoids and azathioprine. In recent years new drugs have been introduced that have opened up the possibilities of treatment. But many pending questions remain, due to the toxicity associated with their use and the possibility of interaction with other drugs, which complicates their use and can compromise the prognoses of these patients. Calcineurin inhibitors and mTOR are the drugs involved with greater frequency in interactions with other drugs, which makes it necessary to anticipate this possibility
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spelling oai:dadun.unav.edu:10171-225942020-03-03T20:15:41Z Monitorización y efectos secundarios de los inmunosupresores en el trasplante Sadaba, B. (Belén) Immunosuppressants Medication interactions ABSTRACT The success of organ transplants and their consideration as a clearly established treatment in some indications is due to the development of immunosuppressant drugs. While it was not the first of the drugs to be employed, the introduction of cyclosporin in the 1980s in immunosuppressant treatment made possible an increase in the number of transplants and the success of this practice. From then onwards, immunosuppression has been based on the use of a combination of drugs, initially cyclosporin, corticoids and azathioprine. In recent years new drugs have been introduced that have opened up the possibilities of treatment. But many pending questions remain, due to the toxicity associated with their use and the possibility of interaction with other drugs, which complicates their use and can compromise the prognoses of these patients. Calcineurin inhibitors and mTOR are the drugs involved with greater frequency in interactions with other drugs, which makes it necessary to anticipate this possibility 2012-06-17T18:40:31Z 2012-06-17T18:40:31Z 2006 info:eu-repo/semantics/article https://hdl.handle.net/10171/22594 spa http://www.cfnavarra.es/salud/anales/textos/vol29/sup2/suple17.html info:eu-repo/semantics/openAccess application/pdf Gobierno de Navarra. Departamento de Salud
spellingShingle Immunosuppressants
Medication interactions
Sadaba, B. (Belén)
Monitorización y efectos secundarios de los inmunosupresores en el trasplante
title Monitorización y efectos secundarios de los inmunosupresores en el trasplante
title_full Monitorización y efectos secundarios de los inmunosupresores en el trasplante
title_fullStr Monitorización y efectos secundarios de los inmunosupresores en el trasplante
title_full_unstemmed Monitorización y efectos secundarios de los inmunosupresores en el trasplante
title_short Monitorización y efectos secundarios de los inmunosupresores en el trasplante
title_sort monitorización y efectos secundarios de los inmunosupresores en el trasplante
topic Immunosuppressants
Medication interactions
url https://hdl.handle.net/10171/22594
work_keys_str_mv AT sadababbelen monitorizacionyefectossecundariosdelosinmunosupresoreseneltrasplante