Evaluation of two different methods for vascular sampling by three-dimensional power Doppler angiography in solid and cystic-solid adnexal masses
Objective To analyze two different methods for performing three-dimensional power Doppler angiography (3D-PDA) vascular sampling in solid and cystic-solid adnexal masses. Methods Twenty-one 3D-PDA volumes from 18 consecutive and unselected solid or cystic-solid adnexal masses (13 malignant and...
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
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Wiley-Blackwell
2012
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| Online Access: | https://hdl.handle.net/10171/22902 |
| _version_ | 1793399925119123456 |
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| author | Alcazar, J.L. (Juan Luis) Prka, M. (M.) |
| author_facet | Alcazar, J.L. (Juan Luis) Prka, M. (M.) |
| author_sort | Alcazar, J.L. (Juan Luis) |
| collection | DSpace |
| description | Objective To analyze two different methods for performing
three-dimensional power Doppler angiography
(3D-PDA) vascular sampling in solid and cystic-solid
adnexal masses.
Methods Twenty-one 3D-PDA volumes from 18 consecutive
and unselected solid or cystic-solid adnexal masses
(13 malignant and five benign) were analyzed. A single
examiner (J. L. A.) acquired all the volumes according to a
predetermined scanning protocol. Two different observers
(one inexperienced and the other experienced) calculated
3D-PDA vascular indices (vascularization index (VI), flow
index (FI) and vascularization flow index (VFI)) from
solid tumor areas. First, manual sampling (Plane A, 15◦
rotation-step) was performed, and 1 week later 5-cm3
sphere sampling from the most vascularized area was carried
out. The observers made a record of any difficulty
that they encountered in delineating the solid areas of
tumors or in distinguishing true tumor vessels from preexisting
vessels, the time spent performing each analysis
was recorded and inter- and intraobserver reproducibility
was evaluated for each method using intraclass correlation
coefficients (ICC).
Results In four (19.0%) of the 21 volumes sphere
sampling could not be performed because it was not
possible to obtain a sphere smaller than 5.5 cm3. This
happened in cases in which image zooming was used when
acquiring the 3D volume. The inexperienced observer
encountered more difficulty, but not significantly more,
than the experienced observer when analyzing 3D-PDA
volumes both by manual sampling (29% vs. 14% of
cases) and 5-cm3 sphere sampling (35% vs. 18% of cases).
The mean time spent by the inexperienced observer was
significantly greater (P < 0.001) than that spent by the
experienced observer both for manual sampling (6.11 min
vs. 1.85 min) and 5-cm3 sphere sampling (2.93 min vs.
2.15 min). Contrary to the findings for the experienced
observer, the inexperienced observer required less time to
perform sphere sampling than they did manual sampling.
Interobserver agreement was high for both methods: ICC
for manual volume, 0.993; manual VI, 0.908; manual
FI, 0.913; manual VFI, 0.914; sphere volume, 0.949;
sphere VI, 0.954; sphere FI 0.850; and sphere VFI, 0.953.
Intraobserver reproducibility was also high, with all ICCs
above 0.99.
Conclusions Manual and 5-cm3 sphere sampling are
reproducible methods for 3D-PDA vascular sampling.
Caution is required when image zoom is used at the time
of acquiring the volume because this may prevent sphere
sampling. Difficulties found in performing both manual
and sphere sampling do not seem to significantly affect the
reproducibility of Doppler index calculations. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-22902 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2012 |
| publisher | Wiley-Blackwell |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-229022022-06-29T09:28:04Z Evaluation of two different methods for vascular sampling by three-dimensional power Doppler angiography in solid and cystic-solid adnexal masses Alcazar, J.L. (Juan Luis) Prka, M. (M.) Doppler Ovarian neoplasms Three-dimensional ultrasound Objective To analyze two different methods for performing three-dimensional power Doppler angiography (3D-PDA) vascular sampling in solid and cystic-solid adnexal masses. Methods Twenty-one 3D-PDA volumes from 18 consecutive and unselected solid or cystic-solid adnexal masses (13 malignant and five benign) were analyzed. A single examiner (J. L. A.) acquired all the volumes according to a predetermined scanning protocol. Two different observers (one inexperienced and the other experienced) calculated 3D-PDA vascular indices (vascularization index (VI), flow index (FI) and vascularization flow index (VFI)) from solid tumor areas. First, manual sampling (Plane A, 15◦ rotation-step) was performed, and 1 week later 5-cm3 sphere sampling from the most vascularized area was carried out. The observers made a record of any difficulty that they encountered in delineating the solid areas of tumors or in distinguishing true tumor vessels from preexisting vessels, the time spent performing each analysis was recorded and inter- and intraobserver reproducibility was evaluated for each method using intraclass correlation coefficients (ICC). Results In four (19.0%) of the 21 volumes sphere sampling could not be performed because it was not possible to obtain a sphere smaller than 5.5 cm3. This happened in cases in which image zooming was used when acquiring the 3D volume. The inexperienced observer encountered more difficulty, but not significantly more, than the experienced observer when analyzing 3D-PDA volumes both by manual sampling (29% vs. 14% of cases) and 5-cm3 sphere sampling (35% vs. 18% of cases). The mean time spent by the inexperienced observer was significantly greater (P < 0.001) than that spent by the experienced observer both for manual sampling (6.11 min vs. 1.85 min) and 5-cm3 sphere sampling (2.93 min vs. 2.15 min). Contrary to the findings for the experienced observer, the inexperienced observer required less time to perform sphere sampling than they did manual sampling. Interobserver agreement was high for both methods: ICC for manual volume, 0.993; manual VI, 0.908; manual FI, 0.913; manual VFI, 0.914; sphere volume, 0.949; sphere VI, 0.954; sphere FI 0.850; and sphere VFI, 0.953. Intraobserver reproducibility was also high, with all ICCs above 0.99. Conclusions Manual and 5-cm3 sphere sampling are reproducible methods for 3D-PDA vascular sampling. Caution is required when image zoom is used at the time of acquiring the volume because this may prevent sphere sampling. Difficulties found in performing both manual and sphere sampling do not seem to significantly affect the reproducibility of Doppler index calculations. 2012-07-17T11:49:16Z 2012-07-17T11:49:16Z 2009 info:eu-repo/semantics/article https://hdl.handle.net/10171/22902 eng info:eu-repo/semantics/openAccess application/pdf Wiley-Blackwell |
| spellingShingle | Doppler Ovarian neoplasms Three-dimensional ultrasound Alcazar, J.L. (Juan Luis) Prka, M. (M.) Evaluation of two different methods for vascular sampling by three-dimensional power Doppler angiography in solid and cystic-solid adnexal masses |
| title | Evaluation of two different methods for vascular sampling by three-dimensional power Doppler angiography in solid and cystic-solid adnexal masses |
| title_full | Evaluation of two different methods for vascular sampling by three-dimensional power Doppler angiography in solid and cystic-solid adnexal masses |
| title_fullStr | Evaluation of two different methods for vascular sampling by three-dimensional power Doppler angiography in solid and cystic-solid adnexal masses |
| title_full_unstemmed | Evaluation of two different methods for vascular sampling by three-dimensional power Doppler angiography in solid and cystic-solid adnexal masses |
| title_short | Evaluation of two different methods for vascular sampling by three-dimensional power Doppler angiography in solid and cystic-solid adnexal masses |
| title_sort | evaluation of two different methods for vascular sampling by three-dimensional power doppler angiography in solid and cystic-solid adnexal masses |
| topic | Doppler Ovarian neoplasms Three-dimensional ultrasound |
| url | https://hdl.handle.net/10171/22902 |
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