Tumor angiogenesis assessed by three-dimensional power Doppler ultrasound in early, advanced and metastatic ovarian cancer: a preliminary study
Objective To evaluate tumor vascularity by threedimensional power Doppler ultrasound (3D-PDU) in early and advanced stage primary ovarian cancers and in metastatic tumors to the ovary. Patients and methods This was a retrospective analysis of clinical and sonographic data from 49 women with pr...
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
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Wiley-Blackwell
2012
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| Online Access: | https://hdl.handle.net/10171/23339 |
| _version_ | 1793399925798600704 |
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| author | Alcazar, J.L. (Juan Luis) |
| author_facet | Alcazar, J.L. (Juan Luis) |
| author_sort | Alcazar, J.L. (Juan Luis) |
| collection | DSpace |
| description | Objective To evaluate tumor vascularity by threedimensional
power Doppler ultrasound (3D-PDU) in
early and advanced stage primary ovarian cancers and
in metastatic tumors to the ovary.
Patients and methods This was a retrospective analysis
of clinical and sonographic data from 49 women
with primary ovarian cancers or metastatic tumors to
the ovary. All women underwent 3D-PDU prior to
surgery. Vascularization index (VI), flow index (FI) and
vascularization flow index (VFI) from solid portions or
papillary projections in the tumors were calculated using
the Virtual Organ Computer-aided AnaLysis (VOCALTM)
program. Definitive histological diagnosis was obtained
in each case.
Results Among the 49 women, 10 had stage I primary
cancers (five low-malignant potential tumors and five
invasive tumors), 26 had advanced stage primary ovarian
cancers and 13 had metastatic tumors to the ovary. Mean
VI and VFI were significantly higher in advanced stage
tumors and metastatic tumors as compared with early
stage tumors. No differences in 3D-PDU indices were
found between advanced stage and metastatic cancers.
Conclusions Vascular indices derived from 3D-PDU tend
to be higher in advanced stage and metastatic ovarian
cancers as compared with early stage ovarian tumors. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-23339 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2012 |
| publisher | Wiley-Blackwell |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-233392022-06-29T09:28:04Z Tumor angiogenesis assessed by three-dimensional power Doppler ultrasound in early, advanced and metastatic ovarian cancer: a preliminary study Alcazar, J.L. (Juan Luis) 3D ultrasound Ovarian cancer Power Doppler Objective To evaluate tumor vascularity by threedimensional power Doppler ultrasound (3D-PDU) in early and advanced stage primary ovarian cancers and in metastatic tumors to the ovary. Patients and methods This was a retrospective analysis of clinical and sonographic data from 49 women with primary ovarian cancers or metastatic tumors to the ovary. All women underwent 3D-PDU prior to surgery. Vascularization index (VI), flow index (FI) and vascularization flow index (VFI) from solid portions or papillary projections in the tumors were calculated using the Virtual Organ Computer-aided AnaLysis (VOCALTM) program. Definitive histological diagnosis was obtained in each case. Results Among the 49 women, 10 had stage I primary cancers (five low-malignant potential tumors and five invasive tumors), 26 had advanced stage primary ovarian cancers and 13 had metastatic tumors to the ovary. Mean VI and VFI were significantly higher in advanced stage tumors and metastatic tumors as compared with early stage tumors. No differences in 3D-PDU indices were found between advanced stage and metastatic cancers. Conclusions Vascular indices derived from 3D-PDU tend to be higher in advanced stage and metastatic ovarian cancers as compared with early stage ovarian tumors. 2012-10-09T11:39:15Z 2012-10-09T11:39:15Z 2006 info:eu-repo/semantics/article https://hdl.handle.net/10171/23339 eng http://onlinelibrary.wiley.com/doi/10.1002/uog.3804/pdf info:eu-repo/semantics/openAccess application/pdf Wiley-Blackwell |
| spellingShingle | 3D ultrasound Ovarian cancer Power Doppler Alcazar, J.L. (Juan Luis) Tumor angiogenesis assessed by three-dimensional power Doppler ultrasound in early, advanced and metastatic ovarian cancer: a preliminary study |
| title | Tumor angiogenesis assessed by three-dimensional power Doppler ultrasound in early, advanced and metastatic ovarian cancer: a preliminary study |
| title_full | Tumor angiogenesis assessed by three-dimensional power Doppler ultrasound in early, advanced and metastatic ovarian cancer: a preliminary study |
| title_fullStr | Tumor angiogenesis assessed by three-dimensional power Doppler ultrasound in early, advanced and metastatic ovarian cancer: a preliminary study |
| title_full_unstemmed | Tumor angiogenesis assessed by three-dimensional power Doppler ultrasound in early, advanced and metastatic ovarian cancer: a preliminary study |
| title_short | Tumor angiogenesis assessed by three-dimensional power Doppler ultrasound in early, advanced and metastatic ovarian cancer: a preliminary study |
| title_sort | tumor angiogenesis assessed by three-dimensional power doppler ultrasound in early, advanced and metastatic ovarian cancer: a preliminary study |
| topic | 3D ultrasound Ovarian cancer Power Doppler |
| url | https://hdl.handle.net/10171/23339 |
| work_keys_str_mv | AT alcazarjljuanluis tumorangiogenesisassessedbythreedimensionalpowerdopplerultrasoundinearlyadvancedandmetastaticovariancancerapreliminarystudy |