Novel sulfonylurea derivatives as H3 receptor antagonists. Preliminary SAR studies

The combination of antagonism at histamine H3 receptor and the stimulation of insulin secretion have been proposed as an approach to new dual therapeutic agents for the treatment of type 2 diabetes mellitus associated with obesity. We have designed and synthesized a new series of non-imidazole deriv...

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Hlavní autoři: Ceras, J. (Javier), Cirauqui, N. (Nuria), Pérez-Silanes, S. (Silvia), Aldana, I. (Ignacio), Monge, A. (Antonio), Galiano, S. (Silvia)
Médium: info:eu-repo/semantics/article
Jazyk:eng
Vydáno: Elsevier 2012
Témata:
On-line přístup:https://hdl.handle.net/10171/23595