Synthesis and antiplasmodial activity of 3-furyl and 3-thienylquinoxaline-2-carbonitrile 1,4-di-N-oxide derivatives

Synthesis and antiplasmodial activity of 3-furyl and 3-thienylquinoxaline-2-carbonitrile 1,4-di-N-oxide derivatives

The aim of this study was to identify new compounds active against Plasmodium falciparum based on our previous research carried out on 3-phenylquinoxaline- 2-carbonitrile 1,4-di-N-oxide derivatives. Twelve compounds were synthesized and evaluated for antimalarial activity. Eight of them showed an...

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Bibliographic Details
Main Authors: Vicente, E. (Esther), Charnaud, S. (Sarah), Bongard, E. (Emily), Raquel, Burguete, A. (Asunción), Solano, B. (Beatriz), Ancizu, S. (Saioa), Pérez-Silanes, S. (Silvia), Aldana, I. (Ignacio), Vivas, L. (Livia), Monge, A. (Antonio)
Format: info:eu-repo/semantics/article
Language:eng
Published: MDPI 2012
Subjects:
Quinoxaline
N-oxides
Malaria
Antiplasmodial
P.falciparum
Online Access:https://hdl.handle.net/10171/23597

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