Studies on log Po/w of quinoxaline di-N-oxides: a comparison of RP-HPLC experimental and predictive approaches.

Studies on log Po/w of quinoxaline di-N-oxides: a comparison of RP-HPLC experimental and predictive approaches.

As reported in our previous papers, a series of quinoxaline-2-carboxamide 1,4-di-N-oxide derivatives were synthesized and studied as anti-tuberculosis agents. Here, the capability of the shake-flask method was studied and the retention time (expressed as log K) of 20 compounds were determined by...

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Bibliographic Details
Main Authors: Moreno-de-Viguri, E. (Elsa), Gabano, E. (Elisabetta), Torres, E. (Enrique), Platts, J.A. (James A.), Ravera, M. (Mauro), Aldana, I. (Ignacio), Monge, A. (Antonio), Pérez-Silanes, S. (Silvia)
Format: info:eu-repo/semantics/article
Language:eng
Published: MDPI 2012
Subjects:
HPLC
Lipophilicity
Log P
Quinoxalines
Online Access:https://hdl.handle.net/10171/23602

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