Synthesis of quinoxaline 1,4-di-N-oxide derivatives on solid support using room temperature and microwave-assisted solvent-free procedures
We describe the synthesis of 12 new ethyl and methyl quinoxaline-7-carboxylate 1,4-di-N-oxide derivatives on solid supports with room temperature and microwave-assisted solvent-free procedures. Results show that solid supports have good catalytic activity in the formation of quinoxaline 1,4-di-N-oxi...
| Main Authors: | , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
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Sociedade Brasileira de Química
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10171/27915 |
| _version_ | 1793400190889099264 |
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| author | Gomez-Caro, L.C. (Lilia C.) Sanchez-Sanchez, M. (Mario) Bocanegra-Garcia, V. (Virgilio) Rivera, G. (Gildardo) Monge, A. (Antonio) |
| author_facet | Gomez-Caro, L.C. (Lilia C.) Sanchez-Sanchez, M. (Mario) Bocanegra-Garcia, V. (Virgilio) Rivera, G. (Gildardo) Monge, A. (Antonio) |
| author_sort | Gomez-Caro, L.C. (Lilia C.) |
| collection | DSpace |
| description | We describe the synthesis of 12 new ethyl and methyl quinoxaline-7-carboxylate 1,4-di-N-oxide derivatives on solid supports with room temperature and microwave-assisted solvent-free procedures. Results show that solid supports have good catalytic activity in the formation of quinoxaline 1,4-di-N-oxide derivatives. We found that florisil and montmorillonite KSF and K10 could be used as new, easily available, inexpensive alternatives of catalysts. Additionally, room temperature and microwave-irradiation solvent-free synthesis was more efficient than a conventional procedure (Beirut reaction), reducing reaction time and increasing yield. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-27915 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2013 |
| publisher | Sociedade Brasileira de Química |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-279152020-03-03T20:36:40Z Synthesis of quinoxaline 1,4-di-N-oxide derivatives on solid support using room temperature and microwave-assisted solvent-free procedures Gomez-Caro, L.C. (Lilia C.) Sanchez-Sanchez, M. (Mario) Bocanegra-Garcia, V. (Virgilio) Rivera, G. (Gildardo) Monge, A. (Antonio) Quinoxaline Solid supports Solvent-free We describe the synthesis of 12 new ethyl and methyl quinoxaline-7-carboxylate 1,4-di-N-oxide derivatives on solid supports with room temperature and microwave-assisted solvent-free procedures. Results show that solid supports have good catalytic activity in the formation of quinoxaline 1,4-di-N-oxide derivatives. We found that florisil and montmorillonite KSF and K10 could be used as new, easily available, inexpensive alternatives of catalysts. Additionally, room temperature and microwave-irradiation solvent-free synthesis was more efficient than a conventional procedure (Beirut reaction), reducing reaction time and increasing yield. 2013-02-20T16:25:22Z 2013-02-20T16:25:22Z 2011 info:eu-repo/semantics/article https://hdl.handle.net/10171/27915 eng info:eu-repo/semantics/openAccess application/pdf Sociedade Brasileira de Química |
| spellingShingle | Quinoxaline Solid supports Solvent-free Gomez-Caro, L.C. (Lilia C.) Sanchez-Sanchez, M. (Mario) Bocanegra-Garcia, V. (Virgilio) Rivera, G. (Gildardo) Monge, A. (Antonio) Synthesis of quinoxaline 1,4-di-N-oxide derivatives on solid support using room temperature and microwave-assisted solvent-free procedures |
| title | Synthesis of quinoxaline 1,4-di-N-oxide derivatives on solid support using room temperature and microwave-assisted solvent-free procedures |
| title_full | Synthesis of quinoxaline 1,4-di-N-oxide derivatives on solid support using room temperature and microwave-assisted solvent-free procedures |
| title_fullStr | Synthesis of quinoxaline 1,4-di-N-oxide derivatives on solid support using room temperature and microwave-assisted solvent-free procedures |
| title_full_unstemmed | Synthesis of quinoxaline 1,4-di-N-oxide derivatives on solid support using room temperature and microwave-assisted solvent-free procedures |
| title_short | Synthesis of quinoxaline 1,4-di-N-oxide derivatives on solid support using room temperature and microwave-assisted solvent-free procedures |
| title_sort | synthesis of quinoxaline 1,4-di-n-oxide derivatives on solid support using room temperature and microwave-assisted solvent-free procedures |
| topic | Quinoxaline Solid supports Solvent-free |
| url | https://hdl.handle.net/10171/27915 |
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