Liberación controlada de principios activos mediante el empleo de formulaciones galénicas

Drugs inside a conventional galenic form are distributed between specific biological targets and other anatomical tissues. With the aim to obtain a more rational and a better therapeutic, one of the most promising possibilities by using the concept of vector- ization: association of an active princi...

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Bibliographic Details
Main Authors: Murillo, M. (M.), Espuelas, S. (Socorro), Prior, S. (Sandra), Vitas, A.I. (Ana Isabel), Renedo, M.J. (María Jesús), Goñi-Leza, M.M. (María del Mar), Irache, J.M. (Juan Manuel), Gamazo, C. (Carlos)
Format: info:eu-repo/semantics/article
Language:spa
Published: Servicio de Publicaciones de la Universidad de Navarra 2013
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Online Access:https://hdl.handle.net/10171/29345
Description
Summary:Drugs inside a conventional galenic form are distributed between specific biological targets and other anatomical tissues. With the aim to obtain a more rational and a better therapeutic, one of the most promising possibilities by using the concept of vector- ization: association of an active principle to an appropriate vector with the object to increase its action efficiency and efficacy. By this means, they do not just increase the affinity of the drug to the target but also active principle gets protected from a potentially hos- tile environment (hydrolytic enzymes, acid pH, etc.). The success in the extension of the applications of the vectorización depends more and more of an appropriate design, for what the fundamental objective of this revision will be the one of presenting the general char- acteristics and some of the current applications in these new galenic forms.