An easy and direct method for the synthesis of 1,2,4-triazole derivatives through carboxylic acids and hydrazinophthalazine
We have developed an easy method for the synthesis of thirteen compounds derived from 1,2,4-triazoles through a carboxylic acid and hydrazinophthalazine reaction, with a 75-85% yield mediated by the use of agents such as 1-ethyl-3-(3'-dimethylaminopropyl)-carbodiimide hydrochloride and 1-hydrox...
| Main Authors: | , , , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
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Sociedade Brasileira de Química
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10171/29496 |
| _version_ | 1793400191126077440 |
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| author | Rivera, G. (Gildardo) Bocanegra-Garcia, V. (Virgilio) Moreno-Herrera, A. (Antonio) Galiano, S. (Silvia) Pérez-Silanes, S. (Silvia) Aldana, I. (Ignacio) Monge, A. (Antonio) |
| author_facet | Rivera, G. (Gildardo) Bocanegra-Garcia, V. (Virgilio) Moreno-Herrera, A. (Antonio) Galiano, S. (Silvia) Pérez-Silanes, S. (Silvia) Aldana, I. (Ignacio) Monge, A. (Antonio) |
| author_sort | Rivera, G. (Gildardo) |
| collection | DSpace |
| description | We have developed an easy method for the synthesis of thirteen compounds derived from 1,2,4-triazoles through a carboxylic acid and hydrazinophthalazine reaction, with a 75-85% yield mediated by the use of agents such as 1-ethyl-3-(3'-dimethylaminopropyl)-carbodiimide hydrochloride and 1-hydroxybenzotriazole. The operational simplicity of this method and the good yield of products make it valuable for the synthesis of new compounds with pharmacological activity. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-29496 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2013 |
| publisher | Sociedade Brasileira de Química |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-294962023-06-05T09:31:03Z An easy and direct method for the synthesis of 1,2,4-triazole derivatives through carboxylic acids and hydrazinophthalazine Rivera, G. (Gildardo) Bocanegra-Garcia, V. (Virgilio) Moreno-Herrera, A. (Antonio) Galiano, S. (Silvia) Pérez-Silanes, S. (Silvia) Aldana, I. (Ignacio) Monge, A. (Antonio) 1,2,4-triazoles Carboxylic acids Hydrazinophthalazine We have developed an easy method for the synthesis of thirteen compounds derived from 1,2,4-triazoles through a carboxylic acid and hydrazinophthalazine reaction, with a 75-85% yield mediated by the use of agents such as 1-ethyl-3-(3'-dimethylaminopropyl)-carbodiimide hydrochloride and 1-hydroxybenzotriazole. The operational simplicity of this method and the good yield of products make it valuable for the synthesis of new compounds with pharmacological activity. 2013-07-05T12:05:36Z 2013-07-05T12:05:36Z 2008 info:eu-repo/semantics/article https://hdl.handle.net/10171/29496 eng info:eu-repo/semantics/openAccess application/pdf Sociedade Brasileira de Química |
| spellingShingle | 1,2,4-triazoles Carboxylic acids Hydrazinophthalazine Rivera, G. (Gildardo) Bocanegra-Garcia, V. (Virgilio) Moreno-Herrera, A. (Antonio) Galiano, S. (Silvia) Pérez-Silanes, S. (Silvia) Aldana, I. (Ignacio) Monge, A. (Antonio) An easy and direct method for the synthesis of 1,2,4-triazole derivatives through carboxylic acids and hydrazinophthalazine |
| title | An easy and direct method for the synthesis of 1,2,4-triazole derivatives through carboxylic acids and hydrazinophthalazine |
| title_full | An easy and direct method for the synthesis of 1,2,4-triazole derivatives through carboxylic acids and hydrazinophthalazine |
| title_fullStr | An easy and direct method for the synthesis of 1,2,4-triazole derivatives through carboxylic acids and hydrazinophthalazine |
| title_full_unstemmed | An easy and direct method for the synthesis of 1,2,4-triazole derivatives through carboxylic acids and hydrazinophthalazine |
| title_short | An easy and direct method for the synthesis of 1,2,4-triazole derivatives through carboxylic acids and hydrazinophthalazine |
| title_sort | easy and direct method for the synthesis of 1,2,4-triazole derivatives through carboxylic acids and hydrazinophthalazine |
| topic | 1,2,4-triazoles Carboxylic acids Hydrazinophthalazine |
| url | https://hdl.handle.net/10171/29496 |
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