Characterization of a native polysaccharide hapten from Brucella melitensis
The 13C nuclear magnetic resonance spectrum of Brucella melitensis native polysaccharide hapten proved to be very similar to that generated by the O-specific chain (PS) isolated from B. melitensis lipopolysaccharide; that is, to a linear polymer in which the repeating unit is composed of five N-form...
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
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American Society for Microbiology
2013
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| Online Access: | https://hdl.handle.net/10171/29522 |
| _version_ | 1793400150988685312 |
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| author | Moreno, E. (Edgardo) Mayer, H. (Hubert) Moriyon, I. (Ignacio) |
| author_facet | Moreno, E. (Edgardo) Mayer, H. (Hubert) Moriyon, I. (Ignacio) |
| author_sort | Moreno, E. (Edgardo) |
| collection | DSpace |
| description | The 13C nuclear magnetic resonance spectrum of Brucella melitensis native polysaccharide hapten proved to be very similar to that generated by the O-specific chain (PS) isolated from B. melitensis lipopolysaccharide; that is, to a linear polymer in which the repeating unit is composed of five N-formylperosaminyl residues, one of them being substituted at position C-3 and the other four at position C-2. The serological analysis suggests that the so-called A determinant is present solely in Brucella abortus PS, the M determinant is only in B. melitensis PS, and the extensive cross-reaction observed is due to a determinant shared by both polysaccharides. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-29522 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2013 |
| publisher | American Society for Microbiology |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-295222020-03-03T20:45:32Z Characterization of a native polysaccharide hapten from Brucella melitensis Moreno, E. (Edgardo) Mayer, H. (Hubert) Moriyon, I. (Ignacio) Antigens, bacterial isolation and purification Brucella immunology Polysaccharides Bacterial immunology The 13C nuclear magnetic resonance spectrum of Brucella melitensis native polysaccharide hapten proved to be very similar to that generated by the O-specific chain (PS) isolated from B. melitensis lipopolysaccharide; that is, to a linear polymer in which the repeating unit is composed of five N-formylperosaminyl residues, one of them being substituted at position C-3 and the other four at position C-2. The serological analysis suggests that the so-called A determinant is present solely in Brucella abortus PS, the M determinant is only in B. melitensis PS, and the extensive cross-reaction observed is due to a determinant shared by both polysaccharides. 2013-07-19T12:47:16Z 2013-07-19T12:47:16Z 1987 info:eu-repo/semantics/article https://hdl.handle.net/10171/29522 eng info:eu-repo/semantics/openAccess application/pdf American Society for Microbiology |
| spellingShingle | Antigens, bacterial isolation and purification Brucella immunology Polysaccharides Bacterial immunology Moreno, E. (Edgardo) Mayer, H. (Hubert) Moriyon, I. (Ignacio) Characterization of a native polysaccharide hapten from Brucella melitensis |
| title | Characterization of a native polysaccharide hapten from Brucella melitensis |
| title_full | Characterization of a native polysaccharide hapten from Brucella melitensis |
| title_fullStr | Characterization of a native polysaccharide hapten from Brucella melitensis |
| title_full_unstemmed | Characterization of a native polysaccharide hapten from Brucella melitensis |
| title_short | Characterization of a native polysaccharide hapten from Brucella melitensis |
| title_sort | characterization of a native polysaccharide hapten from brucella melitensis |
| topic | Antigens, bacterial isolation and purification Brucella immunology Polysaccharides Bacterial immunology |
| url | https://hdl.handle.net/10171/29522 |
| work_keys_str_mv | AT morenoeedgardo characterizationofanativepolysaccharidehaptenfrombrucellamelitensis AT mayerhhubert characterizationofanativepolysaccharidehaptenfrombrucellamelitensis AT moriyoniignacio characterizationofanativepolysaccharidehaptenfrombrucellamelitensis |