New antagonist agents of Neuropeptide Y receptors

In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists mill be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as ant...

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Main Authors: Aldana, I. (Ignacio), Rivero, I. (Isabel), Rivero, A. (Argimiro), Huenchuñir, P. (Patricio), Frigola, C. (Carmen), Alonso, M.L. (María Luisa), Monge, A. (Antonio)
Format: info:eu-repo/semantics/article
Language:eng
Published: Sociedade Brasileira de Química 2013
Subjects:
Online Access:https://hdl.handle.net/10171/29641
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author Aldana, I. (Ignacio)
Rivero, I. (Isabel)
Rivero, A. (Argimiro)
Huenchuñir, P. (Patricio)
Frigola, C. (Carmen)
Alonso, M.L. (María Luisa)
Monge, A. (Antonio)
author_facet Aldana, I. (Ignacio)
Rivero, I. (Isabel)
Rivero, A. (Argimiro)
Huenchuñir, P. (Patricio)
Frigola, C. (Carmen)
Alonso, M.L. (María Luisa)
Monge, A. (Antonio)
author_sort Aldana, I. (Ignacio)
collection DSpace
description In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists mill be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as antagonists of rNPY.
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spelling oai:dadun.unav.edu:10171-296412020-03-04T00:23:02Z New antagonist agents of Neuropeptide Y receptors Aldana, I. (Ignacio) Rivero, I. (Isabel) Rivero, A. (Argimiro) Huenchuñir, P. (Patricio) Frigola, C. (Carmen) Alonso, M.L. (María Luisa) Monge, A. (Antonio) Obesity Energy metabolism Weight reduction Neuropeptide Y In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists mill be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as antagonists of rNPY. 2013-08-31T12:29:42Z 2013-08-31T12:29:42Z 2000 info:eu-repo/semantics/article https://hdl.handle.net/10171/29641 eng info:eu-repo/semantics/openAccess application/pdf Sociedade Brasileira de Química
spellingShingle Obesity
Energy metabolism
Weight reduction
Neuropeptide Y
Aldana, I. (Ignacio)
Rivero, I. (Isabel)
Rivero, A. (Argimiro)
Huenchuñir, P. (Patricio)
Frigola, C. (Carmen)
Alonso, M.L. (María Luisa)
Monge, A. (Antonio)
New antagonist agents of Neuropeptide Y receptors
title New antagonist agents of Neuropeptide Y receptors
title_full New antagonist agents of Neuropeptide Y receptors
title_fullStr New antagonist agents of Neuropeptide Y receptors
title_full_unstemmed New antagonist agents of Neuropeptide Y receptors
title_short New antagonist agents of Neuropeptide Y receptors
title_sort new antagonist agents of neuropeptide y receptors
topic Obesity
Energy metabolism
Weight reduction
Neuropeptide Y
url https://hdl.handle.net/10171/29641
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