New antagonist agents of Neuropeptide Y receptors
In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists mill be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as ant...
Main Authors: | , , , , , , |
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Format: | info:eu-repo/semantics/article |
Language: | eng |
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Sociedade Brasileira de Química
2013
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Online Access: | https://hdl.handle.net/10171/29641 |
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author | Aldana, I. (Ignacio) Rivero, I. (Isabel) Rivero, A. (Argimiro) Huenchuñir, P. (Patricio) Frigola, C. (Carmen) Alonso, M.L. (María Luisa) Monge, A. (Antonio) |
author_facet | Aldana, I. (Ignacio) Rivero, I. (Isabel) Rivero, A. (Argimiro) Huenchuñir, P. (Patricio) Frigola, C. (Carmen) Alonso, M.L. (María Luisa) Monge, A. (Antonio) |
author_sort | Aldana, I. (Ignacio) |
collection | DSpace |
description | In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists mill be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as antagonists of rNPY. |
format | info:eu-repo/semantics/article |
id | oai:dadun.unav.edu:10171-29641 |
institution | Universidad de Navarra |
language | eng |
publishDate | 2013 |
publisher | Sociedade Brasileira de Química |
record_format | dspace |
spelling | oai:dadun.unav.edu:10171-296412020-03-04T00:23:02Z New antagonist agents of Neuropeptide Y receptors Aldana, I. (Ignacio) Rivero, I. (Isabel) Rivero, A. (Argimiro) Huenchuñir, P. (Patricio) Frigola, C. (Carmen) Alonso, M.L. (María Luisa) Monge, A. (Antonio) Obesity Energy metabolism Weight reduction Neuropeptide Y In the CNS, NPY has been implicated in obesity and feeding, endocrine function and metabolism. Potent and selective rNPY antagonists mill be able to probe the merits of this approach for the treatment of obesity. We report the synthesis and preliminary evaluation of some hydrazide derivatives as antagonists of rNPY. 2013-08-31T12:29:42Z 2013-08-31T12:29:42Z 2000 info:eu-repo/semantics/article https://hdl.handle.net/10171/29641 eng info:eu-repo/semantics/openAccess application/pdf Sociedade Brasileira de Química |
spellingShingle | Obesity Energy metabolism Weight reduction Neuropeptide Y Aldana, I. (Ignacio) Rivero, I. (Isabel) Rivero, A. (Argimiro) Huenchuñir, P. (Patricio) Frigola, C. (Carmen) Alonso, M.L. (María Luisa) Monge, A. (Antonio) New antagonist agents of Neuropeptide Y receptors |
title | New antagonist agents of Neuropeptide Y receptors |
title_full | New antagonist agents of Neuropeptide Y receptors |
title_fullStr | New antagonist agents of Neuropeptide Y receptors |
title_full_unstemmed | New antagonist agents of Neuropeptide Y receptors |
title_short | New antagonist agents of Neuropeptide Y receptors |
title_sort | new antagonist agents of neuropeptide y receptors |
topic | Obesity Energy metabolism Weight reduction Neuropeptide Y |
url | https://hdl.handle.net/10171/29641 |
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