Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial

Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial

BACKGROUND: The Fas apoptotic pathway has been implicated in type 2 diabetes and cardiovascular disease. Although a polymorphism (rs7138803; G > A) near the Fas apoptotic inhibitory molecule 2 (FAIM2) locus has been related to obesity, its association with other cardiovascular risk factors and...

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Main Authors: Corella, D. (Dolores), Sorli, J.V. (Jose V.), Gonzalez, J.I. (José I.), Ortega, C. (Carolina), Fito, M. (Montserrat), Bullo, M. (Monica), Martinez-Gonzalez, M.A. (Miguel Ángel), Ros, E. (Emilio), Aros, F. (Fernando), Lapetra, J. (José), Gomez-Gracia, E. (Enrique), Serra-Majem, L. (Luis), Ruiz-Gutierrez, V. (Valentina), Fiol, M. (Miquel), Coltell, O. (Oscar), Vinyoles, E. (Ernest), Pinto, X. (Xavier), Marti-del-Moral, A. (Amelia), Saiz, C. (Carmen), Ordovas, J.M. (Jose Maria), Estruch, R. (Ramón)
Format: info:eu-repo/semantics/article
Language:eng
Published: BioMed Central 2014
Subjects:
Heart rate
FAIM2
Apoptosis
Online Access:https://hdl.handle.net/10171/35558

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