Mediterranean alcohol-drinking pattern and mortality in the SUN (Seguimiento Universidad de Navarra) Project: a prospective cohort study

Moderate alcohol intake has been related to lower mortality. However, alcohol use includes other dimensions beyond the amount of alcohol consumed. These aspects have not been sufficiently studied as a comprehensive entity. We aimed to test the relationship between an overall alcohol-drinking pattern...

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Main Authors: Gea, A. (Alfredo), Bes-Rastrollo, M. (Maira), Toledo, E. (Estefanía), Garcia-Lopez, M. (Martín), Beunza, J.J. (Juan José), Estruch, R. (Ramón), Martinez-Gonzalez, M.A. (Miguel Ángel)
Format: info:eu-repo/semantics/article
Language:eng
Published: Cambridge University Press 2014
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Online Access:https://hdl.handle.net/10171/35909
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author Gea, A. (Alfredo)
Bes-Rastrollo, M. (Maira)
Toledo, E. (Estefanía)
Garcia-Lopez, M. (Martín)
Beunza, J.J. (Juan José)
Estruch, R. (Ramón)
Martinez-Gonzalez, M.A. (Miguel Ángel)
author_facet Gea, A. (Alfredo)
Bes-Rastrollo, M. (Maira)
Toledo, E. (Estefanía)
Garcia-Lopez, M. (Martín)
Beunza, J.J. (Juan José)
Estruch, R. (Ramón)
Martinez-Gonzalez, M.A. (Miguel Ángel)
author_sort Gea, A. (Alfredo)
collection DSpace
description Moderate alcohol intake has been related to lower mortality. However, alcohol use includes other dimensions beyond the amount of alcohol consumed. These aspects have not been sufficiently studied as a comprehensive entity. We aimed to test the relationship between an overall alcohol-drinking pattern and all-cause mortality. In a Mediterranean cohort study, we followed 18394 Spanish participants up to 12 years. A validated 136-item FFQ was used to assess baseline alcohol intake. We developed a score assessing simultaneously seven aspects of alcohol consumption to capture the conformity to a traditional Mediterranean alcohol-drinking pattern (MADP). It positively scored moderate alcohol intake, alcohol intake spread out over the week, low spirit consumption, wine preference, red wine consumption, wine consumed during meals and avoidance of binge drinking. During the follow-up, 206 deaths were identified. For each 2-point increment in a 0-9 score of adherence to the MADP, we observed a 25% relative risk reduction in mortality (95% CI 11, 38%). Within each category of alcohol intake, a higher adherence to the MADP was associated with lower mortality. Abstainers (excluded from the calculations of the MADP) exhibited higher mortality (hazard ratio 1 center dot 82, 95% CI 1 center dot 14, 2 center dot 90) than participants highly adherent to the MADP. In conclusion, better adherence to an overall healthy alcohol-drinking pattern was associated with reduced mortality when compared with abstention or departure from this pattern. This reduction goes beyond the inverse association usually observed for moderate alcohol drinking. Even moderate drinkers can benefit from the advice to follow a traditional MADP.
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spelling oai:dadun.unav.edu:10171-359092022-06-29T09:41:37Z Mediterranean alcohol-drinking pattern and mortality in the SUN (Seguimiento Universidad de Navarra) Project: a prospective cohort study Gea, A. (Alfredo) Bes-Rastrollo, M. (Maira) Toledo, E. (Estefanía) Garcia-Lopez, M. (Martín) Beunza, J.J. (Juan José) Estruch, R. (Ramón) Martinez-Gonzalez, M.A. (Miguel Ángel) Cohort studies Alcohol Drinking patterns Mortality Moderate alcohol intake has been related to lower mortality. However, alcohol use includes other dimensions beyond the amount of alcohol consumed. These aspects have not been sufficiently studied as a comprehensive entity. We aimed to test the relationship between an overall alcohol-drinking pattern and all-cause mortality. In a Mediterranean cohort study, we followed 18394 Spanish participants up to 12 years. A validated 136-item FFQ was used to assess baseline alcohol intake. We developed a score assessing simultaneously seven aspects of alcohol consumption to capture the conformity to a traditional Mediterranean alcohol-drinking pattern (MADP). It positively scored moderate alcohol intake, alcohol intake spread out over the week, low spirit consumption, wine preference, red wine consumption, wine consumed during meals and avoidance of binge drinking. During the follow-up, 206 deaths were identified. For each 2-point increment in a 0-9 score of adherence to the MADP, we observed a 25% relative risk reduction in mortality (95% CI 11, 38%). Within each category of alcohol intake, a higher adherence to the MADP was associated with lower mortality. Abstainers (excluded from the calculations of the MADP) exhibited higher mortality (hazard ratio 1 center dot 82, 95% CI 1 center dot 14, 2 center dot 90) than participants highly adherent to the MADP. In conclusion, better adherence to an overall healthy alcohol-drinking pattern was associated with reduced mortality when compared with abstention or departure from this pattern. This reduction goes beyond the inverse association usually observed for moderate alcohol drinking. Even moderate drinkers can benefit from the advice to follow a traditional MADP. 2014-05-20T12:01:11Z 2014-05-20T12:01:11Z 2014 info:eu-repo/semantics/article https://hdl.handle.net/10171/35909 eng info:eu-repo/semantics/openAccess application/pdf Cambridge University Press
spellingShingle Cohort studies
Alcohol
Drinking patterns
Mortality
Gea, A. (Alfredo)
Bes-Rastrollo, M. (Maira)
Toledo, E. (Estefanía)
Garcia-Lopez, M. (Martín)
Beunza, J.J. (Juan José)
Estruch, R. (Ramón)
Martinez-Gonzalez, M.A. (Miguel Ángel)
Mediterranean alcohol-drinking pattern and mortality in the SUN (Seguimiento Universidad de Navarra) Project: a prospective cohort study
title Mediterranean alcohol-drinking pattern and mortality in the SUN (Seguimiento Universidad de Navarra) Project: a prospective cohort study
title_full Mediterranean alcohol-drinking pattern and mortality in the SUN (Seguimiento Universidad de Navarra) Project: a prospective cohort study
title_fullStr Mediterranean alcohol-drinking pattern and mortality in the SUN (Seguimiento Universidad de Navarra) Project: a prospective cohort study
title_full_unstemmed Mediterranean alcohol-drinking pattern and mortality in the SUN (Seguimiento Universidad de Navarra) Project: a prospective cohort study
title_short Mediterranean alcohol-drinking pattern and mortality in the SUN (Seguimiento Universidad de Navarra) Project: a prospective cohort study
title_sort mediterranean alcohol-drinking pattern and mortality in the sun (seguimiento universidad de navarra) project: a prospective cohort study
topic Cohort studies
Alcohol
Drinking patterns
Mortality
url https://hdl.handle.net/10171/35909
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