Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet

This study presents a new dietary strategy, the RESMENA diet, to combat the comorbidities of the MetS and compares it with following a diet based on the AHA guidelines. The RESMENA diet proved to be more effective throughout a self-control period, where the participants had to apply on their own pre...

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Main Authors: Iglesia, R. (Rocío) de la, Martinez, J.A. (José Alfredo), Zulet, M.A. (María Ángeles)
Format: info:eu-repo/semantics/doctoralThesis
Language:eng
spa
Published: Servicio de Publicaciones de la Universidad de Navarra 2015
Subjects:
Online Access:https://hdl.handle.net/10171/37245
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author Iglesia, R. (Rocío) de la
Martinez, J.A. (José Alfredo)
Zulet, M.A. (María Ángeles)
author_facet Iglesia, R. (Rocío) de la
Martinez, J.A. (José Alfredo)
Zulet, M.A. (María Ángeles)
author_sort Iglesia, R. (Rocío) de la
collection DSpace
description This study presents a new dietary strategy, the RESMENA diet, to combat the comorbidities of the MetS and compares it with following a diet based on the AHA guidelines. The RESMENA diet proved to be more effective throughout a self-control period, where the participants had to apply on their own previous acquired dietary habits, regarding body composition, especially central obesity, and by reducing transaminase levels and maintaining uric acid and serum glucose levels in patients with MetS. Among people suffering MetS with hyperglycaemia, the RESMENA diet showed more benefits than the AHA diet concerning android fat mass reduction and improvement of the general oxidative stress status. Moreover, this investigation evidenced how fibre, TAC, vitamin C, tocopherols, lycopene and fruits are the dietary components that most contributed to improve the MetS related parameters. Furthermore, a link between the recently discovered myokine irisin and several lipid profile biomarkers was reported, suggesting a response of this myokine to atherogenic burdens or a resistance phenomenon. Finally, different dietary antioxidants were proposed to enhance the PON1 ARE activity by epigenetic regulation, lowering the PON1 gene methylation levels.
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spelling oai:dadun.unav.edu:10171-372452020-03-03T13:54:23Z Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet Iglesia, R. (Rocío) de la Martinez, J.A. (José Alfredo) Zulet, M.A. (María Ángeles) Antioxidantes en los alimentos Nutrientes Metabolismo energético Materias Investigacion::Farmacia This study presents a new dietary strategy, the RESMENA diet, to combat the comorbidities of the MetS and compares it with following a diet based on the AHA guidelines. The RESMENA diet proved to be more effective throughout a self-control period, where the participants had to apply on their own previous acquired dietary habits, regarding body composition, especially central obesity, and by reducing transaminase levels and maintaining uric acid and serum glucose levels in patients with MetS. Among people suffering MetS with hyperglycaemia, the RESMENA diet showed more benefits than the AHA diet concerning android fat mass reduction and improvement of the general oxidative stress status. Moreover, this investigation evidenced how fibre, TAC, vitamin C, tocopherols, lycopene and fruits are the dietary components that most contributed to improve the MetS related parameters. Furthermore, a link between the recently discovered myokine irisin and several lipid profile biomarkers was reported, suggesting a response of this myokine to atherogenic burdens or a resistance phenomenon. Finally, different dietary antioxidants were proposed to enhance the PON1 ARE activity by epigenetic regulation, lowering the PON1 gene methylation levels. 2015-01-09T09:54:35Z 2015-01-09T09:54:35Z 2014 2014-06-27 info:eu-repo/semantics/doctoralThesis https://hdl.handle.net/10171/37245 eng spa info:eu-repo/semantics/openAccess application/pdf Servicio de Publicaciones de la Universidad de Navarra
spellingShingle Antioxidantes en los alimentos
Nutrientes
Metabolismo energético
Materias Investigacion::Farmacia
Iglesia, R. (Rocío) de la
Martinez, J.A. (José Alfredo)
Zulet, M.A. (María Ángeles)
Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet
title Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet
title_full Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet
title_fullStr Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet
title_full_unstemmed Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet
title_short Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet
title_sort effects of a new dietary strategy in the treatment of the metabolic syndrome: the resmena diet
topic Antioxidantes en los alimentos
Nutrientes
Metabolismo energético
Materias Investigacion::Farmacia
url https://hdl.handle.net/10171/37245
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AT martinezjajosealfredo effectsofanewdietarystrategyinthetreatmentofthemetabolicsyndrometheresmenadiet
AT zuletmamariaangeles effectsofanewdietarystrategyinthetreatmentofthemetabolicsyndrometheresmenadiet