Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet
This study presents a new dietary strategy, the RESMENA diet, to combat the comorbidities of the MetS and compares it with following a diet based on the AHA guidelines. The RESMENA diet proved to be more effective throughout a self-control period, where the participants had to apply on their own pre...
Main Authors: | , , |
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Format: | info:eu-repo/semantics/doctoralThesis |
Language: | eng spa |
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Servicio de Publicaciones de la Universidad de Navarra
2015
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Online Access: | https://hdl.handle.net/10171/37245 |
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author | Iglesia, R. (Rocío) de la Martinez, J.A. (José Alfredo) Zulet, M.A. (María Ángeles) |
author_facet | Iglesia, R. (Rocío) de la Martinez, J.A. (José Alfredo) Zulet, M.A. (María Ángeles) |
author_sort | Iglesia, R. (Rocío) de la |
collection | DSpace |
description | This study presents a new dietary strategy, the RESMENA diet, to combat the comorbidities of the MetS and compares it with following a diet based on the AHA guidelines. The RESMENA diet proved to be more effective throughout a self-control period, where the participants had to apply on their own previous acquired dietary habits, regarding body composition, especially central obesity, and by reducing transaminase levels and maintaining uric acid and serum glucose levels in patients with MetS. Among people suffering MetS with hyperglycaemia, the RESMENA diet showed more benefits than the AHA diet concerning android fat mass reduction and improvement of the general oxidative stress status.
Moreover, this investigation evidenced how fibre, TAC, vitamin C, tocopherols, lycopene and fruits are the dietary components that most contributed to improve the MetS related parameters. Furthermore, a link between the recently discovered myokine irisin and several lipid profile biomarkers was reported, suggesting a response of this myokine to atherogenic burdens or a resistance phenomenon. Finally, different dietary antioxidants were proposed to enhance the PON1 ARE activity by epigenetic regulation, lowering the PON1 gene methylation levels. |
format | info:eu-repo/semantics/doctoralThesis |
id | oai:dadun.unav.edu:10171-37245 |
institution | Universidad de Navarra |
language | eng spa |
publishDate | 2015 |
publisher | Servicio de Publicaciones de la Universidad de Navarra |
record_format | dspace |
spelling | oai:dadun.unav.edu:10171-372452020-03-03T13:54:23Z Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet Iglesia, R. (Rocío) de la Martinez, J.A. (José Alfredo) Zulet, M.A. (María Ángeles) Antioxidantes en los alimentos Nutrientes Metabolismo energético Materias Investigacion::Farmacia This study presents a new dietary strategy, the RESMENA diet, to combat the comorbidities of the MetS and compares it with following a diet based on the AHA guidelines. The RESMENA diet proved to be more effective throughout a self-control period, where the participants had to apply on their own previous acquired dietary habits, regarding body composition, especially central obesity, and by reducing transaminase levels and maintaining uric acid and serum glucose levels in patients with MetS. Among people suffering MetS with hyperglycaemia, the RESMENA diet showed more benefits than the AHA diet concerning android fat mass reduction and improvement of the general oxidative stress status. Moreover, this investigation evidenced how fibre, TAC, vitamin C, tocopherols, lycopene and fruits are the dietary components that most contributed to improve the MetS related parameters. Furthermore, a link between the recently discovered myokine irisin and several lipid profile biomarkers was reported, suggesting a response of this myokine to atherogenic burdens or a resistance phenomenon. Finally, different dietary antioxidants were proposed to enhance the PON1 ARE activity by epigenetic regulation, lowering the PON1 gene methylation levels. 2015-01-09T09:54:35Z 2015-01-09T09:54:35Z 2014 2014-06-27 info:eu-repo/semantics/doctoralThesis https://hdl.handle.net/10171/37245 eng spa info:eu-repo/semantics/openAccess application/pdf Servicio de Publicaciones de la Universidad de Navarra |
spellingShingle | Antioxidantes en los alimentos Nutrientes Metabolismo energético Materias Investigacion::Farmacia Iglesia, R. (Rocío) de la Martinez, J.A. (José Alfredo) Zulet, M.A. (María Ángeles) Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet |
title | Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet |
title_full | Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet |
title_fullStr | Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet |
title_full_unstemmed | Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet |
title_short | Effects of a new dietary strategy in the treatment of the metabolic syndrome: the RESMENA diet |
title_sort | effects of a new dietary strategy in the treatment of the metabolic syndrome: the resmena diet |
topic | Antioxidantes en los alimentos Nutrientes Metabolismo energético Materias Investigacion::Farmacia |
url | https://hdl.handle.net/10171/37245 |
work_keys_str_mv | AT iglesiarrociodela effectsofanewdietarystrategyinthetreatmentofthemetabolicsyndrometheresmenadiet AT martinezjajosealfredo effectsofanewdietarystrategyinthetreatmentofthemetabolicsyndrometheresmenadiet AT zuletmamariaangeles effectsofanewdietarystrategyinthetreatmentofthemetabolicsyndrometheresmenadiet |