Design and in-vitro/in-vivo evaluation in colon cancer cells of targeted oxaliplatin liposomes to epidermal growth factor receptor by conjugation of different ligands
The colorectal cancer (CRC) is one of the main cancers diagnosed in the first world. Oxaliplatin is currently in the first therapeutic line for metastatic CRC treatment. This drug presents a good tolerability and low toxicity in patients. However, it shows a high and irreversible binding to erythroc...
| Main Authors: | , |
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| Format: | info:eu-repo/semantics/doctoralThesis |
| Language: | eng |
| Published: |
Servicio de Publicaciones de la Universidad de Navarra
2015
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10171/38066 |