Dietary [alfa]-linolenic acid, marine [omega]-3 fatty acids, and mortality in a population with high fish consumption: findings from the PREvención con DIeta MEDiterránea (PREDIMED) study

Dietary [alfa]-linolenic acid, marine [omega]-3 fatty acids, and mortality in a population with high fish consumption: findings from the PREvención con DIeta MEDiterránea (PREDIMED) study

Epidemiological evidence suggests a cardioprotective role of a-linolenic acid (ALA), a plant-derived x-3 fatty acid. It is unclear whether ALA is beneficial in a background of high marine x-3 fatty acids (long-chain n-3 polyunsaturated fatty acids) intake. In persons at high cardiovascular risk fr...

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Bibliographic Details
Main Authors: Ros, E. (Emilio), Estruch, R. (Ramón), Martinez-Gonzalez, M.A. (Miguel Ángel), Salas-Salvado, J. (Jordi), Fito, M. (Montserrat), Corella, D. (Dolores), Martinez, J.A. (José Alfredo), Serra-Majem, L. (Luis), Muñoz, M.A. (Miguel Angel), Fiol, M. (Miquel), Aros, F. (Fernando), Sorli, J.V. (Jose V.), Lopez-Sabater, M.C. (M. Carmen), Serra-Mir, M. (Merce), Bullo, M. (Monica), Sanchez-Tainta, A. (Ana), Hu, F.B. (Frank B.), Guasch-Ferre, M. (Marta), Sala-Vila, A. (Aleix)
Format: info:eu-repo/semantics/article
Language:eng
Published: American Heart Association 2016
Subjects:
PREDIMED
Fish consumption
Materias Investigacion::Ciencias de la vida::Metabolismo
Dieta mediterránea
Materias Investigacion::Ciencias de la Salud::Medicina preventiva
Sudden cardiac death
Nutrition
Fatty acid
Online Access:https://hdl.handle.net/10171/40060
Description
Summary:Epidemiological evidence suggests a cardioprotective role of a-linolenic acid (ALA), a plant-derived x-3 fatty acid. It is unclear whether ALA is beneficial in a background of high marine x-3 fatty acids (long-chain n-3 polyunsaturated fatty acids) intake. In persons at high cardiovascular risk from Spain, a country in which fish consumption is customarily high, we investigated whether meeting the International Society for the Study of Fatty Acids and Lipids recommendation for dietary ALA (0.7% of total energy) at baseline was related to all-cause and cardiovascular disease mortality. We also examined the effect of meeting the society’s recommendation for long-chain n-3 polyunsaturated fatty acids (≥500 mg/day).

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