Synthesis and biological evaluation of quinoxaline di-N-oxide derivatives with in vitro trypanocidal activity
Abstract: We report the synthesis and in vitro activity against T. cruzi epimastigotes of 15 novel quinoxaline derivatives. Ten of the derivatives presented IC50 values lower than the reference drugs Nfx and Bzn; four of them standed out with IC50 values lower than 1.5 M. Moreover, unspecific cy...
| Հիմնական հեղինակներ: | , , , , , , , |
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| Ձևաչափ: | info:eu-repo/semantics/article |
| Լեզու: | eng |
| Հրապարակվել է: |
Elsevier
2016
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| Խորագրեր: | |
| Առցանց հասանելիություն: | https://hdl.handle.net/10171/40413 |