Pharmacokinetic/Pharmacodynamic Modelling-Based Translational Approach applied to the Anticancer Drug Gemcitabine in Advanced Pancreatic and Ovarian Cancer
This thesis performs a retrospective evaluation of data generated for the cytotoxic/cytostatic antimetabolite drug gemcitabine along the different phases of drug development. Using these data, and through data analysis and simulations-based translational exercise, a model-based framework in oncol...
| Main Authors: | , |
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| Format: | info:eu-repo/semantics/doctoralThesis |
| Language: | eng |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10171/44870 |