Análisis de nuevas alteraciones genéticas en neoplasias mieloproliferativas crónicas BCR-ABL1 negativas. Desarrollo de un modelo experimental de mutaciones de tipo 1 y tipo 2 en CALR en Caenorhabditis elegans
The genetic events that caused the BCR-ABL1 negative myeloproliferative neoplasms (MPNs) were elusive until 2005. That year, a JAK2 somatic mutation (p.V617F) was described in a significant proportion of patients. Shortly after, mutations in JAK2 exon 12 and in MPL were also described. All of them a...
| Main Authors: | , |
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| Format: | info:eu-repo/semantics/doctoralThesis |
| Language: | spa |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10171/44963 |