| Sažetak: | Background: Emerging evidence suggests a possible etiologic role of certain personality traits (not necessary
dysfunctional) in the risk of depression, but the longitudinal long-term available evidence is currently scarce. We
longitudinally assessed whether 3 common personality traits (competitiveness, tension and dependency) were
associated with the risk of depression after a maximum follow-up of 15 years.
Methods: We assessed 15,604 university graduates free of depression at baseline through a self-administered
questionnaire including personality traits. Simple, Likert-type, questions with 11 possible answers ranging from 0 to
10 were used at baseline to assess the 3 personality traits. We compared participants with high scores (7–10) versus
those with low scores (0–4). New medical diagnoses of depression during follow-up were used as the outcome.
Results: During a median follow-up of 10.1 y, we prospectively identified 902 new medical diagnoses of
depression. The multivariable-adjusted hazard ratios (95% confidence intervals) for depression were 1.85 (1.52–2.24)
for participants with higher baseline tension (7–10 versus 0 to 4), P-trend < 0.001; and 1.23 (1.06–1.44) for high
versus low baseline dependence levels, P-trend = 0.004. Higher levels of competitiveness were marginally associated
with lower risk of depression, with hazard ratio = 0.78 (0.61–1.01), P-trend = 0.105.
Conclusion: A simple scoring system of personality traits shows an independent association with the future
occurrence of depression. This finding underscores, with now prospective evidence, the importance of personality
traits in the aetiology of depression and can provide a clinically useful tool for gathering valid information about
depression-related personality traits.
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