Gene therapy for Dravet Syndrome: Evaluation of adenoviral vectors expressing SCN1A in a new mouse model

Dravet Syndrome (DS) is a severe encephalopathy with infantile onset, characterized by seizures refractory to conventional antiepileptic drugs, increased risk of sudden unexpected death in epilepsy (SUDEP), as well as cognitive, behavioral and motor comorbidities. The vast majority of DS cases are c...

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Bibliographic Details
Main Authors: Mora-Jiménez, L. (Lucía), Hernandez-Alcoceba, R. (Rubén), Ricobaraza, A. (Ana)
Format: info:eu-repo/semantics/doctoralThesis
Language:eng
Published: Universidad de Navarra 2021
Subjects:
Online Access:https://hdl.handle.net/10171/61043