Potenciación de la Inmunoterapia frente al cáncer de pulmón mediante la modulación del microambiente tumoral

Complement C5a has been proposed as a major regulator of myeloid-derived suppressor cells (MDSCs). In this thesis, we aimed to evaluate the mechanisms by which the C5a/C5aR1 axis endows MDSCs with properties that facilitate tumor growth and metastatic spread. Local C5a production in primary tumors s...

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Bibliographic Details
Main Authors: Ortiz-Espinosa, S. (Sergio), Pio, R. (Rubén), Ajona, D. (Daniel)
Format: info:eu-repo/semantics/doctoralThesis
Language:spa
Published: Universidad de Navarra 2021
Subjects:
Online Access:https://hdl.handle.net/10171/61063