Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk

Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk...

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Những tác giả chính: Julibert, A. (Alicia), Bibiloni, M.M. (Maria del Mar), Bouzas, C. (Cristina), Martinez-Gonzalez, M.A. (Miguel Ángel), Salas-Salvado, J. (Jordi), Corella, D. (Dolores), Zomeño, M.D. (María Dolores), Romaguera, D. (Dora), Vioque, J. (Jesús), Alonso-Gomez, A. (Ángel), Wärnberg, J. (Julia), Martinez, A. (Alfredo), Serra-Majem, L. (Luis), Estruch, R. (Ramón), Tinahones, F.J. (Francisco J.), Lapetra, J. (José), Pinto, X. (Xavier), López-Miranda, J. (José), García-Molina, L. (Laura), Gaforio, J.J. (José Juan), Matía-Martín, P. (Pilar), Daimiel, L. (Lidia), Martín-Sánchez, V. (Vicente), Vidal, J. (Josep), Vázquez, C. (Clotilde), Ros, E. (Emilio), Toledo, E. (Estefanía), Becerra-Tomas, N. (Nerea), Portoles, O. (Olga), Perez-Vega, K.A. (Karla Alejandra), Fiol, M. (Miquel), Torres-Collado, L. (Laura), Tojal-Sierra, L. (Lucas), Carabaño-Moral, R. (Rosa), Abete, I. (Itziar), Sanchez-Villegas, A. (Almudena), Casas, R. (Rosa), Bernal-López, M.R. (María Rosa), Santos-Lozano, J.M. (José M.), Galera, A. (Ana), Ugarriza, L. (Lucía), Ruiz-Canela, M. (Miguel), Babio, N. (Nancy), Coltell, O. (Oscar), Schröder, H. (Helmut), Konieczna, J. (Jadwiga), Orozco-Beltrán, D. (Domingo), Sorto-Sánchez, C. (Carolina), Eguaras, S. (Sonia), Barrubés, L. (Laura), Fito, M. (Montserrat), Tur, J.A. (Josep A.), PREDIMED-PLUS Investigators
Định dạng: info:eu-repo/semantics/article
Ngôn ngữ:eng
Được phát hành: MDPI AG 2021
Những chủ đề:
Truy cập trực tuyến:https://hdl.handle.net/10171/62053
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author Julibert, A. (Alicia)
Bibiloni, M.M. (Maria del Mar)
Bouzas, C. (Cristina)
Martinez-Gonzalez, M.A. (Miguel Ángel)
Salas-Salvado, J. (Jordi)
Corella, D. (Dolores)
Zomeño, M.D. (María Dolores)
Romaguera, D. (Dora)
Vioque, J. (Jesús)
Alonso-Gomez, A. (Ángel)
Wärnberg, J. (Julia)
Martinez, A. (Alfredo)
Serra-Majem, L. (Luis)
Estruch, R. (Ramón)
Tinahones, F.J. (Francisco J.)
Lapetra, J. (José)
Pinto, X. (Xavier)
López-Miranda, J. (José)
García-Molina, L. (Laura)
Gaforio, J.J. (José Juan)
Matía-Martín, P. (Pilar)
Daimiel, L. (Lidia)
Martín-Sánchez, V. (Vicente)
Vidal, J. (Josep)
Vázquez, C. (Clotilde)
Ros, E. (Emilio)
Toledo, E. (Estefanía)
Becerra-Tomas, N. (Nerea)
Portoles, O. (Olga)
Perez-Vega, K.A. (Karla Alejandra)
Fiol, M. (Miquel)
Torres-Collado, L. (Laura)
Tojal-Sierra, L. (Lucas)
Carabaño-Moral, R. (Rosa)
Abete, I. (Itziar)
Sanchez-Villegas, A. (Almudena)
Casas, R. (Rosa)
Bernal-López, M.R. (María Rosa)
Santos-Lozano, J.M. (José M.)
Galera, A. (Ana)
Ugarriza, L. (Lucía)
Ruiz-Canela, M. (Miguel)
Babio, N. (Nancy)
Coltell, O. (Oscar)
Schröder, H. (Helmut)
Konieczna, J. (Jadwiga)
Orozco-Beltrán, D. (Domingo)
Sorto-Sánchez, C. (Carolina)
Eguaras, S. (Sonia)
Barrubés, L. (Laura)
Fito, M. (Montserrat)
Tur, J.A. (Josep A.)
PREDIMED-PLUS Investigators
author_facet Julibert, A. (Alicia)
Bibiloni, M.M. (Maria del Mar)
Bouzas, C. (Cristina)
Martinez-Gonzalez, M.A. (Miguel Ángel)
Salas-Salvado, J. (Jordi)
Corella, D. (Dolores)
Zomeño, M.D. (María Dolores)
Romaguera, D. (Dora)
Vioque, J. (Jesús)
Alonso-Gomez, A. (Ángel)
Wärnberg, J. (Julia)
Martinez, A. (Alfredo)
Serra-Majem, L. (Luis)
Estruch, R. (Ramón)
Tinahones, F.J. (Francisco J.)
Lapetra, J. (José)
Pinto, X. (Xavier)
López-Miranda, J. (José)
García-Molina, L. (Laura)
Gaforio, J.J. (José Juan)
Matía-Martín, P. (Pilar)
Daimiel, L. (Lidia)
Martín-Sánchez, V. (Vicente)
Vidal, J. (Josep)
Vázquez, C. (Clotilde)
Ros, E. (Emilio)
Toledo, E. (Estefanía)
Becerra-Tomas, N. (Nerea)
Portoles, O. (Olga)
Perez-Vega, K.A. (Karla Alejandra)
Fiol, M. (Miquel)
Torres-Collado, L. (Laura)
Tojal-Sierra, L. (Lucas)
Carabaño-Moral, R. (Rosa)
Abete, I. (Itziar)
Sanchez-Villegas, A. (Almudena)
Casas, R. (Rosa)
Bernal-López, M.R. (María Rosa)
Santos-Lozano, J.M. (José M.)
Galera, A. (Ana)
Ugarriza, L. (Lucía)
Ruiz-Canela, M. (Miguel)
Babio, N. (Nancy)
Coltell, O. (Oscar)
Schröder, H. (Helmut)
Konieczna, J. (Jadwiga)
Orozco-Beltrán, D. (Domingo)
Sorto-Sánchez, C. (Carolina)
Eguaras, S. (Sonia)
Barrubés, L. (Laura)
Fito, M. (Montserrat)
Tur, J.A. (Josep A.)
PREDIMED-PLUS Investigators
author_sort Julibert, A. (Alicia)
collection DSpace
description Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants (n = 6560, men and women, 55-75 years old, with overweight/obesity and MetS) in the PREvención con DIeta MEDiterránea (PREDIMED)-Plus randomized trial. Methods: Assessment of fat intake (total fat, monounsatured fatty acids: MUFA, polyunsaturated fatty acids: PUFA, saturated fatty acids: SFA, trans-fatty acids: trans-FA, linoleic acid, α-linolenic acid, and ω-3 FA) using a validated food frequency questionnaire, and diet quality using 17-item Mediterranean dietary questionnaire and fat quality index (FQI). Results: Participants in the highest quintile of total dietary fat intake showed lower intake of energy, carbohydrates, protein and fiber, but higher intake of PUFA, MUFA, SFA, TFA, LA, ALA and ω-3 FA. Differences in MetS components were found according to fat intake. Odds (5th vs. 1st quintile): hyperglycemia: 1.3-1.6 times higher for total fat, MUFA, SFA and ω-3 FA intake; low high-density lipoprotein cholesterol (HDL-c): 1.2 higher for LA; hypertriglyceridemia: 0.7 lower for SFA and ω-3 FA intake. Conclusions: Dietary fats played different role on MetS components of high CVD risk patients. Dietary fat intake was associated with higher risk of hyperglycemia.
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publishDate 2021
publisher MDPI AG
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spelling oai:dadun.unav.edu:10171-620532023-05-29T12:38:51Z Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk Julibert, A. (Alicia) Bibiloni, M.M. (Maria del Mar) Bouzas, C. (Cristina) Martinez-Gonzalez, M.A. (Miguel Ángel) Salas-Salvado, J. (Jordi) Corella, D. (Dolores) Zomeño, M.D. (María Dolores) Romaguera, D. (Dora) Vioque, J. (Jesús) Alonso-Gomez, A. (Ángel) Wärnberg, J. (Julia) Martinez, A. (Alfredo) Serra-Majem, L. (Luis) Estruch, R. (Ramón) Tinahones, F.J. (Francisco J.) Lapetra, J. (José) Pinto, X. (Xavier) López-Miranda, J. (José) García-Molina, L. (Laura) Gaforio, J.J. (José Juan) Matía-Martín, P. (Pilar) Daimiel, L. (Lidia) Martín-Sánchez, V. (Vicente) Vidal, J. (Josep) Vázquez, C. (Clotilde) Ros, E. (Emilio) Toledo, E. (Estefanía) Becerra-Tomas, N. (Nerea) Portoles, O. (Olga) Perez-Vega, K.A. (Karla Alejandra) Fiol, M. (Miquel) Torres-Collado, L. (Laura) Tojal-Sierra, L. (Lucas) Carabaño-Moral, R. (Rosa) Abete, I. (Itziar) Sanchez-Villegas, A. (Almudena) Casas, R. (Rosa) Bernal-López, M.R. (María Rosa) Santos-Lozano, J.M. (José M.) Galera, A. (Ana) Ugarriza, L. (Lucía) Ruiz-Canela, M. (Miguel) Babio, N. (Nancy) Coltell, O. (Oscar) Schröder, H. (Helmut) Konieczna, J. (Jadwiga) Orozco-Beltrán, D. (Domingo) Sorto-Sánchez, C. (Carolina) Eguaras, S. (Sonia) Barrubés, L. (Laura) Fito, M. (Montserrat) Tur, J.A. (Josep A.) PREDIMED-PLUS Investigators Materias Investigacion::Ciencias de la Salud::Medicina preventiva Mediterranean diet Cardiovascular disease risk Dietary fat Fat intake Fatty acids Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants (n = 6560, men and women, 55-75 years old, with overweight/obesity and MetS) in the PREvención con DIeta MEDiterránea (PREDIMED)-Plus randomized trial. Methods: Assessment of fat intake (total fat, monounsatured fatty acids: MUFA, polyunsaturated fatty acids: PUFA, saturated fatty acids: SFA, trans-fatty acids: trans-FA, linoleic acid, α-linolenic acid, and ω-3 FA) using a validated food frequency questionnaire, and diet quality using 17-item Mediterranean dietary questionnaire and fat quality index (FQI). Results: Participants in the highest quintile of total dietary fat intake showed lower intake of energy, carbohydrates, protein and fiber, but higher intake of PUFA, MUFA, SFA, TFA, LA, ALA and ω-3 FA. Differences in MetS components were found according to fat intake. Odds (5th vs. 1st quintile): hyperglycemia: 1.3-1.6 times higher for total fat, MUFA, SFA and ω-3 FA intake; low high-density lipoprotein cholesterol (HDL-c): 1.2 higher for LA; hypertriglyceridemia: 0.7 lower for SFA and ω-3 FA intake. Conclusions: Dietary fats played different role on MetS components of high CVD risk patients. Dietary fat intake was associated with higher risk of hyperglycemia. 2021-09-23T09:36:18Z 2021-09-23T09:36:18Z 2019 info:eu-repo/semantics/article https://hdl.handle.net/10171/62053 eng info:eu-repo/grantAgreement/EC/FP7/340918/EU info:eu-repo/semantics/openAccess application/pdf MDPI AG
spellingShingle Materias Investigacion::Ciencias de la Salud::Medicina preventiva
Mediterranean diet
Cardiovascular disease risk
Dietary fat
Fat intake
Fatty acids
Julibert, A. (Alicia)
Bibiloni, M.M. (Maria del Mar)
Bouzas, C. (Cristina)
Martinez-Gonzalez, M.A. (Miguel Ángel)
Salas-Salvado, J. (Jordi)
Corella, D. (Dolores)
Zomeño, M.D. (María Dolores)
Romaguera, D. (Dora)
Vioque, J. (Jesús)
Alonso-Gomez, A. (Ángel)
Wärnberg, J. (Julia)
Martinez, A. (Alfredo)
Serra-Majem, L. (Luis)
Estruch, R. (Ramón)
Tinahones, F.J. (Francisco J.)
Lapetra, J. (José)
Pinto, X. (Xavier)
López-Miranda, J. (José)
García-Molina, L. (Laura)
Gaforio, J.J. (José Juan)
Matía-Martín, P. (Pilar)
Daimiel, L. (Lidia)
Martín-Sánchez, V. (Vicente)
Vidal, J. (Josep)
Vázquez, C. (Clotilde)
Ros, E. (Emilio)
Toledo, E. (Estefanía)
Becerra-Tomas, N. (Nerea)
Portoles, O. (Olga)
Perez-Vega, K.A. (Karla Alejandra)
Fiol, M. (Miquel)
Torres-Collado, L. (Laura)
Tojal-Sierra, L. (Lucas)
Carabaño-Moral, R. (Rosa)
Abete, I. (Itziar)
Sanchez-Villegas, A. (Almudena)
Casas, R. (Rosa)
Bernal-López, M.R. (María Rosa)
Santos-Lozano, J.M. (José M.)
Galera, A. (Ana)
Ugarriza, L. (Lucía)
Ruiz-Canela, M. (Miguel)
Babio, N. (Nancy)
Coltell, O. (Oscar)
Schröder, H. (Helmut)
Konieczna, J. (Jadwiga)
Orozco-Beltrán, D. (Domingo)
Sorto-Sánchez, C. (Carolina)
Eguaras, S. (Sonia)
Barrubés, L. (Laura)
Fito, M. (Montserrat)
Tur, J.A. (Josep A.)
PREDIMED-PLUS Investigators
Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk
title Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk
title_full Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk
title_fullStr Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk
title_full_unstemmed Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk
title_short Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk
title_sort total and subtypes of dietary fat intake and its association with components of the metabolic syndrome in a mediterranean population at high cardiovascular risk
topic Materias Investigacion::Ciencias de la Salud::Medicina preventiva
Mediterranean diet
Cardiovascular disease risk
Dietary fat
Fat intake
Fatty acids
url https://hdl.handle.net/10171/62053
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