Diagnostic accuracy of transvaginal sonography for detecting parametrial involvement in women with deep endometriosis: systematic review and meta-analysis
Objective To evaluate the accuracy of transvaginal sonography (TVS) for detecting parametrial deep endometriosis, using laparoscopy as the reference standard. Methods A search was performed in PubMed/MEDLINE and Web of Science for studies evaluating TVS for detecting parametrial involvement i...
| Main Authors: | , , , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
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Wiley
2022
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| Online Access: | https://hdl.handle.net/10171/62916 |
| _version_ | 1793399931079229440 |
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| author | Guerriero, S. (Stefano) Martínez, L. (L.) Gómez, I. (I.) Pascual, M.A. (Maria Angela) Ajossa, S. (Silvia) Pagliuca, M. (Mariachiara) Alcazar, J.L. (Juan Luis) |
| author_facet | Guerriero, S. (Stefano) Martínez, L. (L.) Gómez, I. (I.) Pascual, M.A. (Maria Angela) Ajossa, S. (Silvia) Pagliuca, M. (Mariachiara) Alcazar, J.L. (Juan Luis) |
| author_sort | Guerriero, S. (Stefano) |
| collection | DSpace |
| description | Objective
To evaluate the accuracy of transvaginal sonography (TVS) for detecting parametrial deep endometriosis, using laparoscopy as the reference standard.
Methods
A search was performed in PubMed/MEDLINE and Web of Science for studies evaluating TVS for detecting parametrial involvement in women with suspected deep endometriosis, as compared with laparoscopy, from January 2000 to December 2020. The Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool was used to evaluate the quality of the studies. Pooled sensitivity, specificity and positive and negative likelihood ratios for TVS in the detection of parametrial deep endometriosis were calculated, and the post-test probability of parametrial deep endometriosis following a positive or negative test was determined.
Results
The search identified 134 citations. Four studies, comprising 560 patients, were included in the analysis. The mean prevalence of parametrial deep endometriosis at surgery was 18%. Overall, the pooled estimated sensitivity, specificity and positive and negative likelihood ratios of TVS in the detection of parametrial deep endometriosis were 31% (95% CI, 10–64%), 98% (95% CI, 95–99%), 18.5 (95% CI, 8.8–38.9) and 0.70 (95% CI, 0.46–1.06), respectively. The diagnostic odds ratio was 26 (95% CI, 10–68). Heterogeneity was high. Visualization of a lesion suspected to be parametrial deep endometriosis on TVS increased significantly the post-test probability of parametrial deep endometriosis.
Conclusion
TVS has high specificity but low sensitivity for the detection of parametrial deep endometriosis. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-62916 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2022 |
| publisher | Wiley |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-629162023-05-22T07:50:16Z Diagnostic accuracy of transvaginal sonography for detecting parametrial involvement in women with deep endometriosis: systematic review and meta-analysis Guerriero, S. (Stefano) Martínez, L. (L.) Gómez, I. (I.) Pascual, M.A. (Maria Angela) Ajossa, S. (Silvia) Pagliuca, M. (Mariachiara) Alcazar, J.L. (Juan Luis) Materias Investigacion::Ciencias de la Salud::Obstetricia y ginecología Endometriosis Parametrium Transvaginal ultrasound Objective To evaluate the accuracy of transvaginal sonography (TVS) for detecting parametrial deep endometriosis, using laparoscopy as the reference standard. Methods A search was performed in PubMed/MEDLINE and Web of Science for studies evaluating TVS for detecting parametrial involvement in women with suspected deep endometriosis, as compared with laparoscopy, from January 2000 to December 2020. The Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool was used to evaluate the quality of the studies. Pooled sensitivity, specificity and positive and negative likelihood ratios for TVS in the detection of parametrial deep endometriosis were calculated, and the post-test probability of parametrial deep endometriosis following a positive or negative test was determined. Results The search identified 134 citations. Four studies, comprising 560 patients, were included in the analysis. The mean prevalence of parametrial deep endometriosis at surgery was 18%. Overall, the pooled estimated sensitivity, specificity and positive and negative likelihood ratios of TVS in the detection of parametrial deep endometriosis were 31% (95% CI, 10–64%), 98% (95% CI, 95–99%), 18.5 (95% CI, 8.8–38.9) and 0.70 (95% CI, 0.46–1.06), respectively. The diagnostic odds ratio was 26 (95% CI, 10–68). Heterogeneity was high. Visualization of a lesion suspected to be parametrial deep endometriosis on TVS increased significantly the post-test probability of parametrial deep endometriosis. Conclusion TVS has high specificity but low sensitivity for the detection of parametrial deep endometriosis. 2022-02-14T13:46:13Z 2022-02-14T13:46:13Z 2021 info:eu-repo/semantics/article https://hdl.handle.net/10171/62916 eng info:eu-repo/semantics/openAccess application/pdf Wiley |
| spellingShingle | Materias Investigacion::Ciencias de la Salud::Obstetricia y ginecología Endometriosis Parametrium Transvaginal ultrasound Guerriero, S. (Stefano) Martínez, L. (L.) Gómez, I. (I.) Pascual, M.A. (Maria Angela) Ajossa, S. (Silvia) Pagliuca, M. (Mariachiara) Alcazar, J.L. (Juan Luis) Diagnostic accuracy of transvaginal sonography for detecting parametrial involvement in women with deep endometriosis: systematic review and meta-analysis |
| title | Diagnostic accuracy of transvaginal sonography for detecting parametrial involvement in women with deep endometriosis: systematic review and meta-analysis |
| title_full | Diagnostic accuracy of transvaginal sonography for detecting parametrial involvement in women with deep endometriosis: systematic review and meta-analysis |
| title_fullStr | Diagnostic accuracy of transvaginal sonography for detecting parametrial involvement in women with deep endometriosis: systematic review and meta-analysis |
| title_full_unstemmed | Diagnostic accuracy of transvaginal sonography for detecting parametrial involvement in women with deep endometriosis: systematic review and meta-analysis |
| title_short | Diagnostic accuracy of transvaginal sonography for detecting parametrial involvement in women with deep endometriosis: systematic review and meta-analysis |
| title_sort | diagnostic accuracy of transvaginal sonography for detecting parametrial involvement in women with deep endometriosis: systematic review and meta-analysis |
| topic | Materias Investigacion::Ciencias de la Salud::Obstetricia y ginecología Endometriosis Parametrium Transvaginal ultrasound |
| url | https://hdl.handle.net/10171/62916 |
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