A Mediterranean lifestyle reduces the risk of cardiovascular disease in the “Seguimiento Universidad de Navarra” (SUN) cohort

Background and aims: A healthy lifestyle is essential to prevent cardiovascular disease (CVD). However, beyond dietary habits, there is a scarcity of studies comprehensively assessing the typical traditional Mediterranean lifestyle with a multi-dimensional index. We assessed the association betwe...

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Main Authors: Mata-Fernández, A. (Arantxa), Hershey-de-la-Cruz, M.S. (María Soledad), Pastrana-Delgado, J. (Juan), Sotos-Prieto, M. (Mercedes), Ruiz-Canela, M. (Miguel), Kales, S.N. (Stefanos N.), Martinez-Gonzalez, M.A. (Miguel Ángel), Fernandez-Montero, A. (Alejandro)
Format: info:eu-repo/semantics/article
Language:eng
Published: Elsevier 2022
Subjects:
Online Access:https://hdl.handle.net/10171/63413
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author Mata-Fernández, A. (Arantxa)
Hershey-de-la-Cruz, M.S. (María Soledad)
Pastrana-Delgado, J. (Juan)
Sotos-Prieto, M. (Mercedes)
Ruiz-Canela, M. (Miguel)
Kales, S.N. (Stefanos N.)
Martinez-Gonzalez, M.A. (Miguel Ángel)
Fernandez-Montero, A. (Alejandro)
author_facet Mata-Fernández, A. (Arantxa)
Hershey-de-la-Cruz, M.S. (María Soledad)
Pastrana-Delgado, J. (Juan)
Sotos-Prieto, M. (Mercedes)
Ruiz-Canela, M. (Miguel)
Kales, S.N. (Stefanos N.)
Martinez-Gonzalez, M.A. (Miguel Ángel)
Fernandez-Montero, A. (Alejandro)
author_sort Mata-Fernández, A. (Arantxa)
collection DSpace
description Background and aims: A healthy lifestyle is essential to prevent cardiovascular disease (CVD). However, beyond dietary habits, there is a scarcity of studies comprehensively assessing the typical traditional Mediterranean lifestyle with a multi-dimensional index. We assessed the association between the Mediterranean lifestyle (measured with the MEDLIFE index including diet, physical activity, and other lifestyle factors) and the incidence of CVD. Methods and results: The “Seguimiento Universidad de Navarra” (SUN) project is a prospective, dynamic and multipurpose cohort of Spanish university graduates. We calculated a MEDLIFE score, composed of 28 items on food consumption, dietary habits, physical activity, rest, social habits, and conviviality, for 18,631 participants by assigning 1 point for each typical Mediterra- nean lifestyle factor achieved, for a theoretically possible final score ranging from 0 to 28 points. During an average follow-up of 11.5 years, 172 CVD cases (myocardial infarction, stroke or cardio- vascular death) were observed. An inverse association between the MEDLIFE score and the risk of primary cardiovascular events was observed, with multivariable-adjusted hazard ratio (HR) Z 0.50; (95% confidence interval, 0.31e0.81) for the highest MEDLIFE scores (14e23 points) compared to the lowest scores (0e9 points), p (trend) Z 0.004. Conclusion: A higher level of adherence to the Mediterranean lifestyle was significantly associ- ated with a lower risk of CVD in a Spanish cohort. Public health strategies should promote the Mediterranean lifestyle to preserve cardiovascular health.
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spelling oai:dadun.unav.edu:10171-634132022-06-29T09:41:40Z A Mediterranean lifestyle reduces the risk of cardiovascular disease in the “Seguimiento Universidad de Navarra” (SUN) cohort Mata-Fernández, A. (Arantxa) Hershey-de-la-Cruz, M.S. (María Soledad) Pastrana-Delgado, J. (Juan) Sotos-Prieto, M. (Mercedes) Ruiz-Canela, M. (Miguel) Kales, S.N. (Stefanos N.) Martinez-Gonzalez, M.A. (Miguel Ángel) Fernandez-Montero, A. (Alejandro) Cardiovascular risk Lifestyle MEDLIFE index Mediterranean lifestyle SUN cohort Background and aims: A healthy lifestyle is essential to prevent cardiovascular disease (CVD). However, beyond dietary habits, there is a scarcity of studies comprehensively assessing the typical traditional Mediterranean lifestyle with a multi-dimensional index. We assessed the association between the Mediterranean lifestyle (measured with the MEDLIFE index including diet, physical activity, and other lifestyle factors) and the incidence of CVD. Methods and results: The “Seguimiento Universidad de Navarra” (SUN) project is a prospective, dynamic and multipurpose cohort of Spanish university graduates. We calculated a MEDLIFE score, composed of 28 items on food consumption, dietary habits, physical activity, rest, social habits, and conviviality, for 18,631 participants by assigning 1 point for each typical Mediterra- nean lifestyle factor achieved, for a theoretically possible final score ranging from 0 to 28 points. During an average follow-up of 11.5 years, 172 CVD cases (myocardial infarction, stroke or cardio- vascular death) were observed. An inverse association between the MEDLIFE score and the risk of primary cardiovascular events was observed, with multivariable-adjusted hazard ratio (HR) Z 0.50; (95% confidence interval, 0.31e0.81) for the highest MEDLIFE scores (14e23 points) compared to the lowest scores (0e9 points), p (trend) Z 0.004. Conclusion: A higher level of adherence to the Mediterranean lifestyle was significantly associ- ated with a lower risk of CVD in a Spanish cohort. Public health strategies should promote the Mediterranean lifestyle to preserve cardiovascular health. 2022-04-25T10:27:33Z 2022-04-25T10:27:33Z 2021 info:eu-repo/semantics/article https://hdl.handle.net/10171/63413 eng info:eu-repo/semantics/openAccess application/pdf Elsevier
spellingShingle Cardiovascular risk
Lifestyle
MEDLIFE index
Mediterranean lifestyle
SUN cohort
Mata-Fernández, A. (Arantxa)
Hershey-de-la-Cruz, M.S. (María Soledad)
Pastrana-Delgado, J. (Juan)
Sotos-Prieto, M. (Mercedes)
Ruiz-Canela, M. (Miguel)
Kales, S.N. (Stefanos N.)
Martinez-Gonzalez, M.A. (Miguel Ángel)
Fernandez-Montero, A. (Alejandro)
A Mediterranean lifestyle reduces the risk of cardiovascular disease in the “Seguimiento Universidad de Navarra” (SUN) cohort
title A Mediterranean lifestyle reduces the risk of cardiovascular disease in the “Seguimiento Universidad de Navarra” (SUN) cohort
title_full A Mediterranean lifestyle reduces the risk of cardiovascular disease in the “Seguimiento Universidad de Navarra” (SUN) cohort
title_fullStr A Mediterranean lifestyle reduces the risk of cardiovascular disease in the “Seguimiento Universidad de Navarra” (SUN) cohort
title_full_unstemmed A Mediterranean lifestyle reduces the risk of cardiovascular disease in the “Seguimiento Universidad de Navarra” (SUN) cohort
title_short A Mediterranean lifestyle reduces the risk of cardiovascular disease in the “Seguimiento Universidad de Navarra” (SUN) cohort
title_sort mediterranean lifestyle reduces the risk of cardiovascular disease in the “seguimiento universidad de navarra” (sun) cohort
topic Cardiovascular risk
Lifestyle
MEDLIFE index
Mediterranean lifestyle
SUN cohort
url https://hdl.handle.net/10171/63413
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