New insights into pathogenesis of acute porphyria attacks and proof-of-concept of augmenting hepatic PBGD as etiological treatment

New insights into pathogenesis of acute porphyria attacks and proof-of-concept of augmenting hepatic PBGD as etiological treatment

Acute Intermittent Porphyria (AIP) is a rare disease caused by a hepatic deficiency of porphobilinogen deaminase (PBGD) and is characterized by acute neurovisceral attacks. Currently, available treatments for AIP are not optimal and do not cover the entire spectrum of symptoms and presentations of t...

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Bibliographic Details
Main Authors: Jericó-Asenjo, D. (Daniel), Fontanellas-Romá, A. (Antonio)
Format: info:eu-repo/semantics/doctoralThesis
Language:eng
Published: Universidad de Navarra 2022
Subjects:
Materias Investigacion::Ciencias de la Salud::Hepatología
Porfiria
Porphyrias
Acute porphyria attacks
Acute neurovisceral attacks
Online Access:https://hdl.handle.net/10171/63816

Internet

https://hdl.handle.net/10171/63816

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