The Mediterranean diet and physical activity: better together than apart for the prevention of premature mortality
Diet and physical activity (PA) have been studied extensively in epidemiology as single or combined lifestyle factors; however, their interaction has not been studied thoroughly. Studying potential synergisms between lifestyle components with a comprehensive interaction analysis, including additive...
| Main Authors: | , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | English |
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2023
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| Online Access: | https://hdl.handle.net/10171/65304 |
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| author | Hershey-de-la-Cruz, M.S. (María Soledad) Martinez-Gonzalez, M.A. (Miguel Ángel) Álvarez-Álvarez, I. (Ismael) Martínez-Hernández, J.A. (J. Alfredo) Ruiz-Canela, M. (Miguel) |
| author_facet | Hershey-de-la-Cruz, M.S. (María Soledad) Martinez-Gonzalez, M.A. (Miguel Ángel) Álvarez-Álvarez, I. (Ismael) Martínez-Hernández, J.A. (J. Alfredo) Ruiz-Canela, M. (Miguel) |
| author_sort | Hershey-de-la-Cruz, M.S. (María Soledad) |
| collection | DSpace |
| description | Diet and physical activity (PA) have been studied extensively in epidemiology as single or combined lifestyle factors; however, their interaction has not been studied thoroughly. Studying potential synergisms between lifestyle components with a comprehensive interaction analysis, including additive measures of interaction, provides key insights into the nature of their joint effect and helps target interventions more effectively. First, a comprehensive review was conducted to assess the potential research gap regarding reported interaction analyses conducted in studies assessing the Mediterranean diet (MedDiet) in combination with PA on all-cause mortality. Thereafter, we prospectively assessed the joint association of the MedDiet with PA on all-cause mortality in the Seguimiento Universidad de Navarra (SUN) cohort, followed by both multiplicative and additive interaction analyses. The conjoint effect of low adherence to the MedDiet and low PA observed an increased risk greater than the individual risk factors, suggesting a potential additive interaction or synergism between both exposures, with relative risk due to interaction (RERI) and (95 % confidence interval (95 % CI)) = 0.46 (-0.83 to 1.75) and attributable proportion (95 % CI) due to interaction of 36 % (-0.62, 1.34). No multiplicative interaction was detected. Studying interactions between lifestyle factors, such as the MedDiet and PA, is particularly relevant given the current research gaps in studying the complexities of combined aspects of lifestyle in comparison with isolated behaviours. Our findings underline the important public health message of adhering to both the MedDiet and PA for the prevention of premature mortality. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-65304 |
| institution | Universidad de Navarra |
| language | English |
| publishDate | 2023 |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-653042023-05-03T12:12:35Z The Mediterranean diet and physical activity: better together than apart for the prevention of premature mortality Hershey-de-la-Cruz, M.S. (María Soledad) Martinez-Gonzalez, M.A. (Miguel Ángel) Álvarez-Álvarez, I. (Ismael) Martínez-Hernández, J.A. (J. Alfredo) Ruiz-Canela, M. (Miguel) Mediterranean diet Physical activity Interactions Additive interaction All-cause mortality Lifestyle factors Diet and physical activity (PA) have been studied extensively in epidemiology as single or combined lifestyle factors; however, their interaction has not been studied thoroughly. Studying potential synergisms between lifestyle components with a comprehensive interaction analysis, including additive measures of interaction, provides key insights into the nature of their joint effect and helps target interventions more effectively. First, a comprehensive review was conducted to assess the potential research gap regarding reported interaction analyses conducted in studies assessing the Mediterranean diet (MedDiet) in combination with PA on all-cause mortality. Thereafter, we prospectively assessed the joint association of the MedDiet with PA on all-cause mortality in the Seguimiento Universidad de Navarra (SUN) cohort, followed by both multiplicative and additive interaction analyses. The conjoint effect of low adherence to the MedDiet and low PA observed an increased risk greater than the individual risk factors, suggesting a potential additive interaction or synergism between both exposures, with relative risk due to interaction (RERI) and (95 % confidence interval (95 % CI)) = 0.46 (-0.83 to 1.75) and attributable proportion (95 % CI) due to interaction of 36 % (-0.62, 1.34). No multiplicative interaction was detected. Studying interactions between lifestyle factors, such as the MedDiet and PA, is particularly relevant given the current research gaps in studying the complexities of combined aspects of lifestyle in comparison with isolated behaviours. Our findings underline the important public health message of adhering to both the MedDiet and PA for the prevention of premature mortality. 2023-02-07T12:58:59Z 2023-02-07T12:58:59Z 2022 info:eu-repo/semantics/article https://hdl.handle.net/10171/65304 en info:eu-repo/grantAgreement/MSC/Redes Temáticas de Investigación Cooperativa en Salud (RETICS)/RD 06%2F0045/ES/ALIMENTACIÓN SALUDABLE EN LA PREVENCIÓN PRIMARIA DE ENFERMEDADES CRÓNICAS: LA RED PREDIMED info:eu-repo/grantAgreement/MINECO/Proyectos de investigación en salud (AE en Salud)/PI13%2F00615/ES/ESTILOS DE VIDA Y RIESGO DE DIABETES MELLITUS GESTACIONAL: LA COHORTE SUN info:eu-repo/grantAgreement/MINECO/Proyectos de investigación en salud (AE Salud 2014)/PI14%2F01668/ES/Dieta y estilos de vida en la prevención de la diabetes mellitus gestacional: un proyecto coordinado de casos y controles y análisis prospectivo de un estudio de cohortes info:eu-repo/grantAgreement/MINECO/Proyectos de investigación en salud (AE Salud 2014)/PI14%2F01798/ES/Patrones de dieta, de actividad física y de consumo de alcohol y riesgo de depresión en la cohorte SUN info:eu-repo/grantAgreement/MINECO/Proyectos de investigación en salud (AE Salud 2014)/PI14%2F01764/ES/Prevención eficiente de la demencia en sujetos con alto riesgo info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016 (ISCIII)/PI17%2F01795/ES/ESTUDIO DE LA OBESIDAD COMO FACTOR DE RIESGO DE MORTALIDAD Y SU PREVENCION MEDIANTE RECOMENDACIONES DIETETICAS: ANALISIS LONGITUDINAL DE LA COHORTE SUN info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI20%2F00564/ES/EMPODERAMIENTO INTEGRAL PARA GANAR SALUD: ANALISIS LONGITUDINAL DE LA COHORTE SUN info:eu-repo/semantics/openAccess application/pdf |
| spellingShingle | Mediterranean diet Physical activity Interactions Additive interaction All-cause mortality Lifestyle factors Hershey-de-la-Cruz, M.S. (María Soledad) Martinez-Gonzalez, M.A. (Miguel Ángel) Álvarez-Álvarez, I. (Ismael) Martínez-Hernández, J.A. (J. Alfredo) Ruiz-Canela, M. (Miguel) The Mediterranean diet and physical activity: better together than apart for the prevention of premature mortality |
| title | The Mediterranean diet and physical activity: better together than apart for the prevention of premature mortality |
| title_full | The Mediterranean diet and physical activity: better together than apart for the prevention of premature mortality |
| title_fullStr | The Mediterranean diet and physical activity: better together than apart for the prevention of premature mortality |
| title_full_unstemmed | The Mediterranean diet and physical activity: better together than apart for the prevention of premature mortality |
| title_short | The Mediterranean diet and physical activity: better together than apart for the prevention of premature mortality |
| title_sort | mediterranean diet and physical activity: better together than apart for the prevention of premature mortality |
| topic | Mediterranean diet Physical activity Interactions Additive interaction All-cause mortality Lifestyle factors |
| url | https://hdl.handle.net/10171/65304 |
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