Association between Polyphenol Intake and Gastric Cancer Risk by Anatomic and Histologic Subtypes: MCC-Spain

Abstract: Several anticancer properties have been largely attributed to phenolics in in vivo and in vitro studies, but epidemiologic evidence is still scarce. Furthermore, some classes have not been studied in relation to gastric cancer (GC). The aim of this study was to assess the relationship betw...

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Main Authors: Rubín-García, M. (María), Vitelli-Storelli, F. (Facundo), Molina, A.J. (Antonio José), Zamora-Ros, R. (Raúl), Aragonés, N. (Nuria), Adarnaz, E. (Eva), Castaño-Vinyals, G. (Gemma), Obón-Santacana, M. (Mireia), Gómez-Acebo, I. (Inés), Molina-Barceló, A. (Ana), Fernández-Tardón, G. (Guillermo), Jiménez-Moleón, J.J. (José Juan), Alguacil, J. (Juan), Chirlaque, M.D. (María-Dolores), Toledo, E. (Estefanía), Gómez, B. (Beatriz), Pollán, M. (Marina), Kogevinas, M. (Manolis), Martin, V. (Vicente)
Format: info:eu-repo/semantics/article
Language:eng
Published: MDPI 2023
Subjects:
Online Access:https://hdl.handle.net/10171/65505
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author Rubín-García, M. (María)
Vitelli-Storelli, F. (Facundo)
Molina, A.J. (Antonio José)
Zamora-Ros, R. (Raúl)
Aragonés, N. (Nuria)
Adarnaz, E. (Eva)
Castaño-Vinyals, G. (Gemma)
Obón-Santacana, M. (Mireia)
Gómez-Acebo, I. (Inés)
Molina-Barceló, A. (Ana)
Fernández-Tardón, G. (Guillermo)
Jiménez-Moleón, J.J. (José Juan)
Alguacil, J. (Juan)
Chirlaque, M.D. (María-Dolores)
Toledo, E. (Estefanía)
Gómez, B. (Beatriz)
Pollán, M. (Marina)
Kogevinas, M. (Manolis)
Martin, V. (Vicente)
author_facet Rubín-García, M. (María)
Vitelli-Storelli, F. (Facundo)
Molina, A.J. (Antonio José)
Zamora-Ros, R. (Raúl)
Aragonés, N. (Nuria)
Adarnaz, E. (Eva)
Castaño-Vinyals, G. (Gemma)
Obón-Santacana, M. (Mireia)
Gómez-Acebo, I. (Inés)
Molina-Barceló, A. (Ana)
Fernández-Tardón, G. (Guillermo)
Jiménez-Moleón, J.J. (José Juan)
Alguacil, J. (Juan)
Chirlaque, M.D. (María-Dolores)
Toledo, E. (Estefanía)
Gómez, B. (Beatriz)
Pollán, M. (Marina)
Kogevinas, M. (Manolis)
Martin, V. (Vicente)
author_sort Rubín-García, M. (María)
collection DSpace
description Abstract: Several anticancer properties have been largely attributed to phenolics in in vivo and in vitro studies, but epidemiologic evidence is still scarce. Furthermore, some classes have not been studied in relation to gastric cancer (GC). The aim of this study was to assess the relationship between the intake of phenolic acids, stilbenes, and other phenolics and the risk of developing GC and its anatomical and histological subtypes. We used data from a multi-case-control study (MCC-Spain) obtained from different regions of Spain. We included 2700 controls and 329 GC cases. Odds ratios (ORs) were calculated using mixed effects logistic regression considering quartiles of phenolic intake.
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publisher MDPI
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spelling oai:dadun.unav.edu:10171-655052023-07-10T05:16:48Z Association between Polyphenol Intake and Gastric Cancer Risk by Anatomic and Histologic Subtypes: MCC-Spain Rubín-García, M. (María) Vitelli-Storelli, F. (Facundo) Molina, A.J. (Antonio José) Zamora-Ros, R. (Raúl) Aragonés, N. (Nuria) Adarnaz, E. (Eva) Castaño-Vinyals, G. (Gemma) Obón-Santacana, M. (Mireia) Gómez-Acebo, I. (Inés) Molina-Barceló, A. (Ana) Fernández-Tardón, G. (Guillermo) Jiménez-Moleón, J.J. (José Juan) Alguacil, J. (Juan) Chirlaque, M.D. (María-Dolores) Toledo, E. (Estefanía) Gómez, B. (Beatriz) Pollán, M. (Marina) Kogevinas, M. (Manolis) Martin, V. (Vicente) Diet Epidemiology Gastric cancer Polyphenols Phenolic acids Stilbenes Lignans Anatomic Histologic MCC-Spain Abstract: Several anticancer properties have been largely attributed to phenolics in in vivo and in vitro studies, but epidemiologic evidence is still scarce. Furthermore, some classes have not been studied in relation to gastric cancer (GC). The aim of this study was to assess the relationship between the intake of phenolic acids, stilbenes, and other phenolics and the risk of developing GC and its anatomical and histological subtypes. We used data from a multi-case-control study (MCC-Spain) obtained from different regions of Spain. We included 2700 controls and 329 GC cases. Odds ratios (ORs) were calculated using mixed effects logistic regression considering quartiles of phenolic intake. 2023-02-20T09:16:20Z 2023-02-20T09:16:20Z 2020 info:eu-repo/semantics/article https://hdl.handle.net/10171/65505 eng info:eu-repo/grantAgreement/MICINN/Proyectos de investigación en salud/PS09/00773/ES/ESTUDIO MULTICASO-CONTROL DE BASE POBLACIONAL (CANCER DE MAMA, CANCER COLORRECTAL, CANCER GASTRO-ESOFAGICO Y CANCER DE PROSTATA) info:eu-repo/grantAgreement/MICINN/Proyectos de investigación en salud/PS09/01286/ES/ESTUDIO MULTICASO-CONTROL DE BASE POBLACIONAL (CANCER DE MAMA, CANCER COLORRECTAL, CANCER GASTRO-ESOFAGICO Y CANCER DE PROSTATA) info:eu-repo/grantAgreement/MICINN/Proyectos de investigación en salud/PS09/02078/ES/ESTUDIO MULTICASO-CONTROL DE BASE POBLACIONAL (CANCER DE MAMA, CANCER COLORRECTAL, CANCER GASTRO-ESOFAGICO Y CANCER DE PROSTATA) info:eu-repo/grantAgreement/MICINN/Proyectos de investigación en salud/PS09/01662/ESTUDIO MULTICASO-CONTROL DE BASE POBLACIONAL (CANCER DE MAMA, CANCER COLORRECTAL, CANCER GASTRO-ESOFAGICO Y CANCER DE PROSTATA) info:eu-repo/grantAgreement/MICINN/Proyectos de Investigación en Salud/PI11/01403/ES/Etiopatogenia del cáncer gástrico en España: Posible interacción microbiano-ambiental en un estudio multicéntrico de casos y controles de base poblacional (MCC-Spain Gastric Cancer) info:eu-repo/grantAgreement/MICINN/Proyectos de Investigación en Salud/PI11/01889/ES/Estudio epidemiológico sobre el trabajo nocturno, disrupción del ritmo circadiano, susceptibilidad genética y riesgo de cáncer de mama y próstata info:eu-repo/grantAgreement/MICINN/Proyectos de Investigación en Salud/PI11/00226/ES/Riesgo de cáncer colorrectal en España por carcinógenos en agua de consumo info:eu-repo/grantAgreement/MICINN/Proyectos de Investigación en Salud/PI11/01810/ES/Factores de riesgo ambientales, infecciosos y genéticos asociados a la leucemia linfática crónica (LLC), en el marco del estudio Multi-Caso-Control (MCC-SPAIN) info:eu-repo/grantAgreement/MICINN/Proyectos de Investigación en Salud/PI11/02213/ES/ESTUDIO MULTICASO-CONTROL DE BASE POBLACIONAL (CÁNCER DE MAMA y LLC) info:eu-repo/grantAgreement/MINECO/Proyectos de investigación en salud (AE Salud 2014)/PI14/01219/ES/Perfil molecular del envejecimiento en la patogénesis y pronóstico de la leucemia linfática crónica info:eu-repo/grantAgreement/MINECO/Proyectos de investigación en salud (Modalidad proyectos de investigación en salud) (AES 2015)/PI15/00069/ES/Integración de big data genéticos y datos clínicos: supervivencia con cáncer de mama en el estudio MCC-Spain info:eu-repo/grantAgreement/MINECO/Proyectos de investigación en salud (Modalidad proyectos de investigación en salud) (AES 2015)/PI15/00914/ES/INTEGRACIÓN DE BIG DATA GENÉTICOS Y DATOS CLÍNICOS: SUPERVIVENCIA Y CALIDAD DE VIDA EN PARTICIPANTES CON CÁNCER DE PRÓSTATA EN EL ESTUDIO MCC-Spain info:eu-repo/grantAgreement/MINECO/Proyectos de investigación en salud (Modalidad proyectos de investigación en salud) (AES 2015)/PI15/01032/ES/Supervivencia de cáncer colorrectal en el proyecto MCC-Spain: Modelos de predicción que integran datos genéticos y clínico-epidemiológicos info:eu-repo/grantAgreement/MINECO/Redes Temáticas de Investigación Cooperativa en Salud (RETICS)/RD12/0036/0036/ES/Cáncer info:eu-repo/semantics/openAccess application/pdf MDPI
spellingShingle Diet
Epidemiology
Gastric cancer
Polyphenols
Phenolic acids
Stilbenes
Lignans
Anatomic
Histologic
MCC-Spain
Rubín-García, M. (María)
Vitelli-Storelli, F. (Facundo)
Molina, A.J. (Antonio José)
Zamora-Ros, R. (Raúl)
Aragonés, N. (Nuria)
Adarnaz, E. (Eva)
Castaño-Vinyals, G. (Gemma)
Obón-Santacana, M. (Mireia)
Gómez-Acebo, I. (Inés)
Molina-Barceló, A. (Ana)
Fernández-Tardón, G. (Guillermo)
Jiménez-Moleón, J.J. (José Juan)
Alguacil, J. (Juan)
Chirlaque, M.D. (María-Dolores)
Toledo, E. (Estefanía)
Gómez, B. (Beatriz)
Pollán, M. (Marina)
Kogevinas, M. (Manolis)
Martin, V. (Vicente)
Association between Polyphenol Intake and Gastric Cancer Risk by Anatomic and Histologic Subtypes: MCC-Spain
title Association between Polyphenol Intake and Gastric Cancer Risk by Anatomic and Histologic Subtypes: MCC-Spain
title_full Association between Polyphenol Intake and Gastric Cancer Risk by Anatomic and Histologic Subtypes: MCC-Spain
title_fullStr Association between Polyphenol Intake and Gastric Cancer Risk by Anatomic and Histologic Subtypes: MCC-Spain
title_full_unstemmed Association between Polyphenol Intake and Gastric Cancer Risk by Anatomic and Histologic Subtypes: MCC-Spain
title_short Association between Polyphenol Intake and Gastric Cancer Risk by Anatomic and Histologic Subtypes: MCC-Spain
title_sort association between polyphenol intake and gastric cancer risk by anatomic and histologic subtypes: mcc-spain
topic Diet
Epidemiology
Gastric cancer
Polyphenols
Phenolic acids
Stilbenes
Lignans
Anatomic
Histologic
MCC-Spain
url https://hdl.handle.net/10171/65505
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