Macronutrient quality index and cardiovascular disease risk in the Seguimiento Universidad de Navarra (SUN) cohort
Purpose To assess the association between a multi-dimensional Macronutrient Quality Index (MQI) and the risk of cardiovascular disease (CVD) in a Mediterranean cohort. Methods Prospective analyses among 18,418 participants (mean age 36 years, 60.8% women) of the Seguimiento Universidad de Navarra (S...
| Main Authors: | , , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | English |
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2023
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| Online Access: | https://hdl.handle.net/10171/66038 |
| _version_ | 1793400183667556352 |
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| author | Vanegas, P. (Paola) Zazpe, I. (Itziar) Santiago, S. (Susana) Fernández-Lázaro, C.I. (César I.) De-la-O-Pascual, V. (Víctor) Martinez-Gonzalez, M.A. (Miguel Ángel) |
| author_facet | Vanegas, P. (Paola) Zazpe, I. (Itziar) Santiago, S. (Susana) Fernández-Lázaro, C.I. (César I.) De-la-O-Pascual, V. (Víctor) Martinez-Gonzalez, M.A. (Miguel Ángel) |
| author_sort | Vanegas, P. (Paola) |
| collection | DSpace |
| description | Purpose To assess the association between a multi-dimensional Macronutrient Quality Index (MQI) and the risk of cardiovascular disease (CVD) in a Mediterranean cohort. Methods Prospective analyses among 18,418 participants (mean age 36 years, 60.8% women) of the Seguimiento Universidad de Navarra (SUN) cohort. Dietary intake information was obtained through a validated semi-quantitative food-frequency questionnaire (FFQ). The MQI (expressing high-quality macronutrient intake) was calculated based on three previously reported quality indices: the Carbohydrate Quality Index (CQI), the Fat Quality Index (FQI), and the Healthy Plate Protein source Quality Index (HPPQI). Adherence to the Mediterranean diet (MedDiet) and Provegetarian Diet was evaluated using the Trichopoulou index and the score proposed by Martinez-Gonzalez, respectively. CVD was defined as new-onset stroke, myocardial infarction, or CVD death. Results After a median follow-up time of 14 years (211,744 person-years), 171 cases of CVD were identified. A significant inverse association was found between the MQI and CVD risk with multivariable-adjusted HR for the highest vs. the lowest quartile of 0.60 (95% IC, 0.38-0.96; P-trend = 0.024). Conclusion In this Mediterranean cohort, we found a significant inverse relationship between a multidimensional MQI (expressing high-quality macronutrient intake) and a lower risk of CVD. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-66038 |
| institution | Universidad de Navarra |
| language | English |
| publishDate | 2023 |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-660382023-07-10T05:17:09Z Macronutrient quality index and cardiovascular disease risk in the Seguimiento Universidad de Navarra (SUN) cohort Vanegas, P. (Paola) Zazpe, I. (Itziar) Santiago, S. (Susana) Fernández-Lázaro, C.I. (César I.) De-la-O-Pascual, V. (Víctor) Martinez-Gonzalez, M.A. (Miguel Ángel) Macronutrient quality CVD Mediterranean diet Provegetarian diet Cohort Food-frecuency questionnaire Coronary-heart-disease Plant-based diets Fatty-acids Carbohydrate Consumption Prevention Reduction Mortality Protein Purpose To assess the association between a multi-dimensional Macronutrient Quality Index (MQI) and the risk of cardiovascular disease (CVD) in a Mediterranean cohort. Methods Prospective analyses among 18,418 participants (mean age 36 years, 60.8% women) of the Seguimiento Universidad de Navarra (SUN) cohort. Dietary intake information was obtained through a validated semi-quantitative food-frequency questionnaire (FFQ). The MQI (expressing high-quality macronutrient intake) was calculated based on three previously reported quality indices: the Carbohydrate Quality Index (CQI), the Fat Quality Index (FQI), and the Healthy Plate Protein source Quality Index (HPPQI). Adherence to the Mediterranean diet (MedDiet) and Provegetarian Diet was evaluated using the Trichopoulou index and the score proposed by Martinez-Gonzalez, respectively. CVD was defined as new-onset stroke, myocardial infarction, or CVD death. Results After a median follow-up time of 14 years (211,744 person-years), 171 cases of CVD were identified. A significant inverse association was found between the MQI and CVD risk with multivariable-adjusted HR for the highest vs. the lowest quartile of 0.60 (95% IC, 0.38-0.96; P-trend = 0.024). Conclusion In this Mediterranean cohort, we found a significant inverse relationship between a multidimensional MQI (expressing high-quality macronutrient intake) and a lower risk of CVD. 2023-04-20T08:43:57Z 2023-04-20T08:43:57Z 2022 info:eu-repo/semantics/article https://hdl.handle.net/10171/66038 en https://pubmed.ncbi.nlm.nih.gov/35597843/ info:eu-repo/grantAgreement/MSC/Redes Temáticas de Investigación Cooperativa en Salud (RETICS)/RD 06/0045/ES/Alimentación saludable en la prevención primaria de enfermedades crónicas: la red PREDIMED info:eu-repo/grantAgreement/MINECO/Centros de Investigación Biomédica en Red (CIBER)/CIBER-OBN/ES/Incorporación grupos CIBER fisiopatología de la obesidad y nutrición (CIBER OBN) info:eu-repo/grantAgreement/MINECO/Proyectos de investigación en salud (AE Salud 2014)/PI14/01668/ES/Dieta y estilos de vida en la prevención de la diabetes mellitus gestacional: un proyecto coordinado de casos y controles y análisis prospectivo de un estudio de cohortes info:eu-repo/grantAgreement/MINECO/Proyectos de investigación en salud (AE Salud 2014)/ PI14/01798/ES/Patrones de dieta, de actividad física y de consumo de alcohol y riesgo de depresión en la cohorte SUN info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016 (ISCIII)/ PI17/01795/ES/Estudio de la obesidad como factor de riesgo de mortalidad y su prevención mediante recomendaciones dietéticas: análisis longitudinal de la cohorte SUN info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI20/00564/ES/Empoderamiento integral para ganar salud: análisis longitudinal de la cohorte SUN info:eu-repo/semantics/openAccess application/pdf |
| spellingShingle | Macronutrient quality CVD Mediterranean diet Provegetarian diet Cohort Food-frecuency questionnaire Coronary-heart-disease Plant-based diets Fatty-acids Carbohydrate Consumption Prevention Reduction Mortality Protein Vanegas, P. (Paola) Zazpe, I. (Itziar) Santiago, S. (Susana) Fernández-Lázaro, C.I. (César I.) De-la-O-Pascual, V. (Víctor) Martinez-Gonzalez, M.A. (Miguel Ángel) Macronutrient quality index and cardiovascular disease risk in the Seguimiento Universidad de Navarra (SUN) cohort |
| title | Macronutrient quality index and cardiovascular disease risk in the Seguimiento Universidad de Navarra (SUN) cohort |
| title_full | Macronutrient quality index and cardiovascular disease risk in the Seguimiento Universidad de Navarra (SUN) cohort |
| title_fullStr | Macronutrient quality index and cardiovascular disease risk in the Seguimiento Universidad de Navarra (SUN) cohort |
| title_full_unstemmed | Macronutrient quality index and cardiovascular disease risk in the Seguimiento Universidad de Navarra (SUN) cohort |
| title_short | Macronutrient quality index and cardiovascular disease risk in the Seguimiento Universidad de Navarra (SUN) cohort |
| title_sort | macronutrient quality index and cardiovascular disease risk in the seguimiento universidad de navarra (sun) cohort |
| topic | Macronutrient quality CVD Mediterranean diet Provegetarian diet Cohort Food-frecuency questionnaire Coronary-heart-disease Plant-based diets Fatty-acids Carbohydrate Consumption Prevention Reduction Mortality Protein |
| url | https://hdl.handle.net/10171/66038 |
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