A pharmacometrics model to define docetaxel target in early breast cancer

A pharmacometrics model to define docetaxel target in early breast cancer

Aims: We aimed to study the relation between pharmacokinetics (PK) and pharmacodynamics (PD) of docetaxel in early breast cancer and recommend a target exposure. Methods: A PK/PD study was performed in 27 early breast cancer patients treated with doxorubicin and cyclophosphamide for 4 cycles foll...

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Bibliographic Details
Main Authors: Aldaz, A. (Azucena), Schaiquevich, P. (Paula), Aramendia, J.M. (J.M.)
Format: info:eu-repo/semantics/article
Language:eng
Published: Wiley 2023
Subjects:
Breast cancer
Docetaxel
Pharmacodynamics
Pharmacokinetics
Precision medicine
Online Access:https://hdl.handle.net/10171/66083

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