Metastasis of spindle cell malignant melanoma in gallbladder
Malignant melanoma is an aggressive neoplasm with a high tendency to metastasize. Gastrointestinal metastases, although described in the literature, are infrequent. We present the case of a 51-year-old male patient with a surfcial spreading melanoma stage IIIc with BRAF mutation who presented a ga...
| Main Authors: | , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
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Springer
2023
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10171/66790 |
| _version_ | 1793400046699413504 |
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| author | Arredondo-Montero, J. (Javier) Recreo-Baquedano, A.C. (Ana Cristina) Bronte-Anaut, M. (Mónica) Martin-Calvo, N. (Nerea) |
| author_facet | Arredondo-Montero, J. (Javier) Recreo-Baquedano, A.C. (Ana Cristina) Bronte-Anaut, M. (Mónica) Martin-Calvo, N. (Nerea) |
| author_sort | Arredondo-Montero, J. (Javier) |
| collection | DSpace |
| description | Malignant melanoma is an aggressive neoplasm with a high tendency to metastasize.
Gastrointestinal metastases, although described in the literature, are infrequent. We present the case of a 51-year-old male
patient with a surfcial spreading melanoma stage IIIc with BRAF mutation who presented a gallbladder outgrowth lesion,
compatible with a polyp. A signifcant growth of the lesion was observed in subsequent TC studies and a laparoscopic
cholecystectomy was performed. The anatomopathological study of the specimen confrmed the diagnosis of gallbladder
metastasis due to epithelioid and spindle cell malignant melanoma. The presence of a gallbladder lesion in the context of a
patient diagnosed with melanoma should establish the diagnostic suspicion of metastasis, and an early extension study and
laparoscopic cholecystectomy should be considered. The palliative surgical approach to avoid hepatobiliary symptomatology can be considered. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-66790 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2023 |
| publisher | Springer |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-667902023-07-10T05:17:42Z Metastasis of spindle cell malignant melanoma in gallbladder Arredondo-Montero, J. (Javier) Recreo-Baquedano, A.C. (Ana Cristina) Bronte-Anaut, M. (Mónica) Martin-Calvo, N. (Nerea) Spindle cell Melanoma Gallbladder Malignant melanoma is an aggressive neoplasm with a high tendency to metastasize. Gastrointestinal metastases, although described in the literature, are infrequent. We present the case of a 51-year-old male patient with a surfcial spreading melanoma stage IIIc with BRAF mutation who presented a gallbladder outgrowth lesion, compatible with a polyp. A signifcant growth of the lesion was observed in subsequent TC studies and a laparoscopic cholecystectomy was performed. The anatomopathological study of the specimen confrmed the diagnosis of gallbladder metastasis due to epithelioid and spindle cell malignant melanoma. The presence of a gallbladder lesion in the context of a patient diagnosed with melanoma should establish the diagnostic suspicion of metastasis, and an early extension study and laparoscopic cholecystectomy should be considered. The palliative surgical approach to avoid hepatobiliary symptomatology can be considered. 2023-07-04T11:53:29Z 2023-07-04T11:53:29Z 2022 info:eu-repo/semantics/article https://hdl.handle.net/10171/66790 eng info:eu-repo/semantics/openAccess application/pdf Springer |
| spellingShingle | Spindle cell Melanoma Gallbladder Arredondo-Montero, J. (Javier) Recreo-Baquedano, A.C. (Ana Cristina) Bronte-Anaut, M. (Mónica) Martin-Calvo, N. (Nerea) Metastasis of spindle cell malignant melanoma in gallbladder |
| title | Metastasis of spindle cell malignant melanoma in gallbladder |
| title_full | Metastasis of spindle cell malignant melanoma in gallbladder |
| title_fullStr | Metastasis of spindle cell malignant melanoma in gallbladder |
| title_full_unstemmed | Metastasis of spindle cell malignant melanoma in gallbladder |
| title_short | Metastasis of spindle cell malignant melanoma in gallbladder |
| title_sort | metastasis of spindle cell malignant melanoma in gallbladder |
| topic | Spindle cell Melanoma Gallbladder |
| url | https://hdl.handle.net/10171/66790 |
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