Omalizumab, the innovative biologic that disrupted the market of the treatment of allergic diseases

Omalizumab, the blockbuster monoclonal antibody anti-IgE that revolutionized the market by the disruptive innovation that supposed more than 20 years ago. This biological drug changed the paradigm of the treatment of allergic diseases, particularly severe allergic asthma and chronic spontaneous u...

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Main Authors: Pérez-Herranz, I. (Irene), Carnés-Sánchez, J. (Jerónimo)
Format: info:eu-repo/semantics/bachelorThesis
Language:eng
Published: 2023
Subjects:
Online Access:https://hdl.handle.net/10171/66799
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author Pérez-Herranz, I. (Irene)
Carnés-Sánchez, J. (Jerónimo)
author_facet Pérez-Herranz, I. (Irene)
Carnés-Sánchez, J. (Jerónimo)
author_sort Pérez-Herranz, I. (Irene)
collection DSpace
description Omalizumab, the blockbuster monoclonal antibody anti-IgE that revolutionized the market by the disruptive innovation that supposed more than 20 years ago. This biological drug changed the paradigm of the treatment of allergic diseases, particularly severe allergic asthma and chronic spontaneous urticaria. It opened up a new alternative world of possible treatments, covering the clinical unmet needs of asthmatic patients and creating value for patients who do not respond well to traditional medicines (small-molecules). Its efficacy and safety have been demonstrated in numerous clinical trials and Real-World Evidence. These observations have favoured the life cycle management of the product for new applications, including nasal polyposis and food allergies. However, it is no longer the only biological on the market for the treatment of these pathologies, so how is it possible that after so many years it is still a blue ocean product?
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spelling oai:dadun.unav.edu:10171-667992023-07-10T05:17:33Z Omalizumab, the innovative biologic that disrupted the market of the treatment of allergic diseases Pérez-Herranz, I. (Irene) Carnés-Sánchez, J. (Jerónimo) Materias Investigacion::Ciencias de la vida::Bioquímica Omalizumab Allergic diseases Omalizumab, the blockbuster monoclonal antibody anti-IgE that revolutionized the market by the disruptive innovation that supposed more than 20 years ago. This biological drug changed the paradigm of the treatment of allergic diseases, particularly severe allergic asthma and chronic spontaneous urticaria. It opened up a new alternative world of possible treatments, covering the clinical unmet needs of asthmatic patients and creating value for patients who do not respond well to traditional medicines (small-molecules). Its efficacy and safety have been demonstrated in numerous clinical trials and Real-World Evidence. These observations have favoured the life cycle management of the product for new applications, including nasal polyposis and food allergies. However, it is no longer the only biological on the market for the treatment of these pathologies, so how is it possible that after so many years it is still a blue ocean product? 2023-07-04T13:01:16Z 2023-07-04T13:01:16Z 2022 2023 info:eu-repo/semantics/bachelorThesis https://hdl.handle.net/10171/66799 eng info:eu-repo/semantics/openAccess application/pdf
spellingShingle Materias Investigacion::Ciencias de la vida::Bioquímica
Omalizumab
Allergic diseases
Pérez-Herranz, I. (Irene)
Carnés-Sánchez, J. (Jerónimo)
Omalizumab, the innovative biologic that disrupted the market of the treatment of allergic diseases
title Omalizumab, the innovative biologic that disrupted the market of the treatment of allergic diseases
title_full Omalizumab, the innovative biologic that disrupted the market of the treatment of allergic diseases
title_fullStr Omalizumab, the innovative biologic that disrupted the market of the treatment of allergic diseases
title_full_unstemmed Omalizumab, the innovative biologic that disrupted the market of the treatment of allergic diseases
title_short Omalizumab, the innovative biologic that disrupted the market of the treatment of allergic diseases
title_sort omalizumab, the innovative biologic that disrupted the market of the treatment of allergic diseases
topic Materias Investigacion::Ciencias de la vida::Bioquímica
Omalizumab
Allergic diseases
url https://hdl.handle.net/10171/66799
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