Transvaginal ultrasound versus magnetic resonance imaging for preoperative assessment of myometrial infiltration in patients with low-grade endometrioid endometrial cancer: A systematic review and head-to-head meta-analysis
Purpose: We aimed to compare the diagnostic performance of magnetic resonance imaging (MRI) and transvaginal ultrasound (TVS) for detecting myometrial invasion (MI) in patients with low-grade endometrioid endometrial carcinoma. Methods: A comprehensive search of MEDLINE (Pubmed), Web of Science,...
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
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Wiley
2023
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| Online Access: | https://hdl.handle.net/10171/67930 |
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| author | Tameish, S. (Sara) Florez, N. (Natalia) Pérez-Vidal, J.R. (Juan Ramón) Chen, H. (Hui) Vara, J. (J.) Alcazar, J.L. (Juan Luis) |
| author_facet | Tameish, S. (Sara) Florez, N. (Natalia) Pérez-Vidal, J.R. (Juan Ramón) Chen, H. (Hui) Vara, J. (J.) Alcazar, J.L. (Juan Luis) |
| author_sort | Tameish, S. (Sara) |
| collection | DSpace |
| description | Purpose: We aimed to compare the diagnostic performance of magnetic resonance imaging (MRI) and transvaginal ultrasound (TVS) for detecting myometrial invasion (MI) in patients with low-grade endometrioid endometrial carcinoma.
Methods: A comprehensive search of MEDLINE (Pubmed), Web of Science, Embase and Scopus (from January 1990 to December 2022) was performed for articles comparing TVS and MRI in the evaluation of myometrial infiltration in low-grade (grade 1 or 2) endometrioid endometrial carcinoma in the same group of patients. We used QUADAS-2 tool for assessing the risk of bias of studies.
Results: We found 104 citations in our extensive research. Four articles were ultimately included in the meta-analysis, after excluding 100 reports. All articles were considered low risk of bias in most of the domains assessed in QUADAS-2. We observed that pooled sensitivity and specificity for detecting deep MI were 65% (95% confidence interval [CI] = 54%-75%) and 85% (95% CI = 79%-89%) for MRI, and 71% (95% CI = 63%-78%) and 76% (95% CI = 67%-83%) for TVS, respectively. No statistical differences were found between both imaging techniques (p > 0.05). We observed low heterogeneity for sensitivity and high for specificity regarding TVS; and moderate for both sensitivity and specificity in case of MRI.
Conclusions: The diagnostic performance of TVS and MRI for the evaluation of deep MI in women with low-grade endometrioid endometrial cancer is similar. However, further research is needed as the number of studies is scanty. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-67930 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2023 |
| publisher | Wiley |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-679302023-11-27T06:06:10Z Transvaginal ultrasound versus magnetic resonance imaging for preoperative assessment of myometrial infiltration in patients with low-grade endometrioid endometrial cancer: A systematic review and head-to-head meta-analysis Tameish, S. (Sara) Florez, N. (Natalia) Pérez-Vidal, J.R. (Juan Ramón) Chen, H. (Hui) Vara, J. (J.) Alcazar, J.L. (Juan Luis) Endometrial neoplasms Low-grade endometrioid Magnetic resonance imaging Myometrium infiltration, Transvaginal Ultrasound Purpose: We aimed to compare the diagnostic performance of magnetic resonance imaging (MRI) and transvaginal ultrasound (TVS) for detecting myometrial invasion (MI) in patients with low-grade endometrioid endometrial carcinoma. Methods: A comprehensive search of MEDLINE (Pubmed), Web of Science, Embase and Scopus (from January 1990 to December 2022) was performed for articles comparing TVS and MRI in the evaluation of myometrial infiltration in low-grade (grade 1 or 2) endometrioid endometrial carcinoma in the same group of patients. We used QUADAS-2 tool for assessing the risk of bias of studies. Results: We found 104 citations in our extensive research. Four articles were ultimately included in the meta-analysis, after excluding 100 reports. All articles were considered low risk of bias in most of the domains assessed in QUADAS-2. We observed that pooled sensitivity and specificity for detecting deep MI were 65% (95% confidence interval [CI] = 54%-75%) and 85% (95% CI = 79%-89%) for MRI, and 71% (95% CI = 63%-78%) and 76% (95% CI = 67%-83%) for TVS, respectively. No statistical differences were found between both imaging techniques (p > 0.05). We observed low heterogeneity for sensitivity and high for specificity regarding TVS; and moderate for both sensitivity and specificity in case of MRI. Conclusions: The diagnostic performance of TVS and MRI for the evaluation of deep MI in women with low-grade endometrioid endometrial cancer is similar. However, further research is needed as the number of studies is scanty. 2023-11-21T13:18:02Z 2023-11-21T13:18:02Z 2023 info:eu-repo/semantics/article https://hdl.handle.net/10171/67930 eng info:eu-repo/semantics/openAccess application/pdf Wiley |
| spellingShingle | Endometrial neoplasms Low-grade endometrioid Magnetic resonance imaging Myometrium infiltration, Transvaginal Ultrasound Tameish, S. (Sara) Florez, N. (Natalia) Pérez-Vidal, J.R. (Juan Ramón) Chen, H. (Hui) Vara, J. (J.) Alcazar, J.L. (Juan Luis) Transvaginal ultrasound versus magnetic resonance imaging for preoperative assessment of myometrial infiltration in patients with low-grade endometrioid endometrial cancer: A systematic review and head-to-head meta-analysis |
| title | Transvaginal ultrasound versus magnetic resonance imaging for preoperative assessment of myometrial infiltration in patients with low-grade endometrioid endometrial cancer: A systematic review and head-to-head meta-analysis |
| title_full | Transvaginal ultrasound versus magnetic resonance imaging for preoperative assessment of myometrial infiltration in patients with low-grade endometrioid endometrial cancer: A systematic review and head-to-head meta-analysis |
| title_fullStr | Transvaginal ultrasound versus magnetic resonance imaging for preoperative assessment of myometrial infiltration in patients with low-grade endometrioid endometrial cancer: A systematic review and head-to-head meta-analysis |
| title_full_unstemmed | Transvaginal ultrasound versus magnetic resonance imaging for preoperative assessment of myometrial infiltration in patients with low-grade endometrioid endometrial cancer: A systematic review and head-to-head meta-analysis |
| title_short | Transvaginal ultrasound versus magnetic resonance imaging for preoperative assessment of myometrial infiltration in patients with low-grade endometrioid endometrial cancer: A systematic review and head-to-head meta-analysis |
| title_sort | transvaginal ultrasound versus magnetic resonance imaging for preoperative assessment of myometrial infiltration in patients with low-grade endometrioid endometrial cancer: a systematic review and head-to-head meta-analysis |
| topic | Endometrial neoplasms Low-grade endometrioid Magnetic resonance imaging Myometrium infiltration, Transvaginal Ultrasound |
| url | https://hdl.handle.net/10171/67930 |
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