Mediterranean diet, Dietary Approaches to Stop Hypertension, and Pro-vegetarian dietary pattern in relation to the risk of basal cell carcinoma: a nested case-control study within the Seguimiento Universidad de Navarra (SUN) cohort
Background: The association of dietary pattern with the risk of basal cell carcinoma (BCC) is little understood and has scarcely been investigated. Objectives: We assessed the association of several complete dietary patterns [Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Pr...
| Main Authors: | , , , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
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American Society of Nutrition
2024
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| Online Access: | https://hdl.handle.net/10171/68861 |
| _version_ | 1793400026661126144 |
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| author | Leone, A. (Alessandro) Martin, A. (Alejandro) Sanchez-Bayona, R. (Rodrigo) De-Amicis, R. (Ramona) Bertoli, S. (Simona) Battezzati, A. (Alberto) Bes-Rastrollo, M. (Maira) |
| author_facet | Leone, A. (Alessandro) Martin, A. (Alejandro) Sanchez-Bayona, R. (Rodrigo) De-Amicis, R. (Ramona) Bertoli, S. (Simona) Battezzati, A. (Alberto) Bes-Rastrollo, M. (Maira) |
| author_sort | Leone, A. (Alessandro) |
| collection | DSpace |
| description | Background: The association of dietary pattern with the risk of
basal cell carcinoma (BCC) is little understood and has scarcely been
investigated.
Objectives: We assessed the association of several complete dietary
patterns [Mediterranean, Dietary Approaches to Stop Hypertension
(DASH), and Pro-vegetarian dietary pattern] with the risk of BCC,
conducting a nested case-control study (4 controls for each case).
Methods: Cases and controls were selected from the SUN
(Seguimiento Universidad de Navarra) cohort using risk set sam-
pling. Cases were identified among subjects free of skin cancer at
baseline but who later reported a physician-made BCC diagnosis
during the follow-up period. In the cohort we identified 101 incident
cases of BCC.
Results: In multivariable-adjusted conditional logistic regression
analyses, better adherence to the Mediterranean diet (highest
compared with lowest quintile) was associated with a 72% relative
reduction in the odds of BCC (OR: 0.28; 95% CI: 0.10, 0.77;
Ptrend = 0.014); the DASH diet was associated with a 68% RR
reduction (OR: 0.32; 95% CI: 0.14, 0.76; Ptrend = 0.013) for the
comparison between extreme quintiles. No association was found
between a Pro-vegetarian dietary pattern and BCC. Higher fruit
consumption (highest compared with lowest quintile, OR: 0.27; 95%
CI: 0.11, 0.64; Ptrend < 0.001) and low-fat dairy products (OR: 0.39;
95% CI: 0.16, 0.92; Ptrend = 0.014) were associated with a lower BCC
risk.
Conclusions: Our results suggest that Mediterranean and DASH
dietary patterns may be associated with a lower risk of BCC, but
confirmatory studies are required. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-68861 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2024 |
| publisher | American Society of Nutrition |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-688612024-02-12T06:07:42Z Mediterranean diet, Dietary Approaches to Stop Hypertension, and Pro-vegetarian dietary pattern in relation to the risk of basal cell carcinoma: a nested case-control study within the Seguimiento Universidad de Navarra (SUN) cohort Leone, A. (Alessandro) Martin, A. (Alejandro) Sanchez-Bayona, R. (Rodrigo) De-Amicis, R. (Ramona) Bertoli, S. (Simona) Battezzati, A. (Alberto) Bes-Rastrollo, M. (Maira) Materias Investigacion::Ciencias de la Salud::Medicina preventiva Mediterranean diet DASH diet Pro-vegetarian diet Dietary pattern Basal cell carcinoma Skin cancer Background: The association of dietary pattern with the risk of basal cell carcinoma (BCC) is little understood and has scarcely been investigated. Objectives: We assessed the association of several complete dietary patterns [Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Pro-vegetarian dietary pattern] with the risk of BCC, conducting a nested case-control study (4 controls for each case). Methods: Cases and controls were selected from the SUN (Seguimiento Universidad de Navarra) cohort using risk set sam- pling. Cases were identified among subjects free of skin cancer at baseline but who later reported a physician-made BCC diagnosis during the follow-up period. In the cohort we identified 101 incident cases of BCC. Results: In multivariable-adjusted conditional logistic regression analyses, better adherence to the Mediterranean diet (highest compared with lowest quintile) was associated with a 72% relative reduction in the odds of BCC (OR: 0.28; 95% CI: 0.10, 0.77; Ptrend = 0.014); the DASH diet was associated with a 68% RR reduction (OR: 0.32; 95% CI: 0.14, 0.76; Ptrend = 0.013) for the comparison between extreme quintiles. No association was found between a Pro-vegetarian dietary pattern and BCC. Higher fruit consumption (highest compared with lowest quintile, OR: 0.27; 95% CI: 0.11, 0.64; Ptrend < 0.001) and low-fat dairy products (OR: 0.39; 95% CI: 0.16, 0.92; Ptrend = 0.014) were associated with a lower BCC risk. Conclusions: Our results suggest that Mediterranean and DASH dietary patterns may be associated with a lower risk of BCC, but confirmatory studies are required. 2024-02-07T09:55:27Z 2024-02-07T09:55:27Z 2020 info:eu-repo/semantics/article https://hdl.handle.net/10171/68861 eng info:eu-repo/semantics/openAccess application/pdf American Society of Nutrition |
| spellingShingle | Materias Investigacion::Ciencias de la Salud::Medicina preventiva Mediterranean diet DASH diet Pro-vegetarian diet Dietary pattern Basal cell carcinoma Skin cancer Leone, A. (Alessandro) Martin, A. (Alejandro) Sanchez-Bayona, R. (Rodrigo) De-Amicis, R. (Ramona) Bertoli, S. (Simona) Battezzati, A. (Alberto) Bes-Rastrollo, M. (Maira) Mediterranean diet, Dietary Approaches to Stop Hypertension, and Pro-vegetarian dietary pattern in relation to the risk of basal cell carcinoma: a nested case-control study within the Seguimiento Universidad de Navarra (SUN) cohort |
| title | Mediterranean diet, Dietary Approaches to Stop Hypertension, and Pro-vegetarian dietary pattern in relation to the risk of basal cell carcinoma: a nested case-control study within the Seguimiento Universidad de Navarra (SUN) cohort |
| title_full | Mediterranean diet, Dietary Approaches to Stop Hypertension, and Pro-vegetarian dietary pattern in relation to the risk of basal cell carcinoma: a nested case-control study within the Seguimiento Universidad de Navarra (SUN) cohort |
| title_fullStr | Mediterranean diet, Dietary Approaches to Stop Hypertension, and Pro-vegetarian dietary pattern in relation to the risk of basal cell carcinoma: a nested case-control study within the Seguimiento Universidad de Navarra (SUN) cohort |
| title_full_unstemmed | Mediterranean diet, Dietary Approaches to Stop Hypertension, and Pro-vegetarian dietary pattern in relation to the risk of basal cell carcinoma: a nested case-control study within the Seguimiento Universidad de Navarra (SUN) cohort |
| title_short | Mediterranean diet, Dietary Approaches to Stop Hypertension, and Pro-vegetarian dietary pattern in relation to the risk of basal cell carcinoma: a nested case-control study within the Seguimiento Universidad de Navarra (SUN) cohort |
| title_sort | mediterranean diet, dietary approaches to stop hypertension, and pro-vegetarian dietary pattern in relation to the risk of basal cell carcinoma: a nested case-control study within the seguimiento universidad de navarra (sun) cohort |
| topic | Materias Investigacion::Ciencias de la Salud::Medicina preventiva Mediterranean diet DASH diet Pro-vegetarian diet Dietary pattern Basal cell carcinoma Skin cancer |
| url | https://hdl.handle.net/10171/68861 |
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