Lifestyles and the risk of depression in the “Seguimiento Universidad de Navarra” cohort
Background: Lifestyles are involved in the pathogenesis of depression and many of these factors can be modified for the potential prevention of depression. Our aim was to assess the association between a healthy-lifestyle score, that includes some less-studied lifestyle indicators, and the risk of...
| Main Authors: | , , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | eng |
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Elsevier
2024
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| Online Access: | https://hdl.handle.net/10171/68878 |
| _version_ | 1793400164315037696 |
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| author | Ruiz-Estigarribia, L. (Liz) Martinez-Gonzalez, M.A. (Miguel Ángel) Diaz-Gutierrez, J. (Jesús) Sanchez-Villegas, A. (Almudena) Lahortiga-Ramos, F. (Francisca) Bes-Rastrollo, M. (Maira) |
| author_facet | Ruiz-Estigarribia, L. (Liz) Martinez-Gonzalez, M.A. (Miguel Ángel) Diaz-Gutierrez, J. (Jesús) Sanchez-Villegas, A. (Almudena) Lahortiga-Ramos, F. (Francisca) Bes-Rastrollo, M. (Maira) |
| author_sort | Ruiz-Estigarribia, L. (Liz) |
| collection | DSpace |
| description | Background: Lifestyles are involved in the pathogenesis of depression and many of these factors can be
modified for the potential prevention of depression. Our aim was to assess the association between a
healthy-lifestyle score, that includes some less-studied lifestyle indicators, and the risk of depression.
Methods: We followed 14,908 participants initially free of any history of depression in the “Seguimiento
Universidad de Navarra” (SUN) cohort. Information was collected biennially from 1999 to December
2016. We calculated a healthy-lifestyle score (0–10 points), previously associated with cardioprotection,
by giving one point to each of the following components: never smoking, physical activity (> 20 METs-h/
week), Mediterranean diet adherence ( 4 points), healthy body mass index ( 22 kg/m2
), moderate
alcohol consumption (women 0.1–5 g/d; men 0.1–10 g/d of ethanol), avoidance of binge drinking (never
more than 5 alcoholic drinks in a row), low television exposure ( 2 h/d), short afternoon nap ( 30 min/
day), time spent with friends (>1 h/d) and working at least 40 h/week.
Results: During a median follow-up of 10.4 years, we observed 774 new cases of major depression among
participants initially free of depression. The highest category (8–10 factors) showed a significant inverse
association with a 32% relative risk reduction for depression compared to the lowest category (0–3
factors) (multivariable-adjusted hazard ratio: 0.68; 95% CI:0.49-0.95) (p for trend = 0.010).
Conclusions: Adopting a healthy-lifestyle was associated with a lower risk of incident depression in the
SUN cohort. This index, including ten simple healthy lifestyle habits, may be useful for a more integrative
approach to depression prevention. |
| format | info:eu-repo/semantics/article |
| id | oai:dadun.unav.edu:10171-68878 |
| institution | Universidad de Navarra |
| language | eng |
| publishDate | 2024 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oai:dadun.unav.edu:10171-688782024-02-12T06:07:47Z Lifestyles and the risk of depression in the “Seguimiento Universidad de Navarra” cohort Ruiz-Estigarribia, L. (Liz) Martinez-Gonzalez, M.A. (Miguel Ángel) Diaz-Gutierrez, J. (Jesús) Sanchez-Villegas, A. (Almudena) Lahortiga-Ramos, F. (Francisca) Bes-Rastrollo, M. (Maira) Materias Investigacion::Ciencias de la Salud::Medicina preventiva Affective disorder Unipolar depression Epidemiology Background: Lifestyles are involved in the pathogenesis of depression and many of these factors can be modified for the potential prevention of depression. Our aim was to assess the association between a healthy-lifestyle score, that includes some less-studied lifestyle indicators, and the risk of depression. Methods: We followed 14,908 participants initially free of any history of depression in the “Seguimiento Universidad de Navarra” (SUN) cohort. Information was collected biennially from 1999 to December 2016. We calculated a healthy-lifestyle score (0–10 points), previously associated with cardioprotection, by giving one point to each of the following components: never smoking, physical activity (> 20 METs-h/ week), Mediterranean diet adherence ( 4 points), healthy body mass index ( 22 kg/m2 ), moderate alcohol consumption (women 0.1–5 g/d; men 0.1–10 g/d of ethanol), avoidance of binge drinking (never more than 5 alcoholic drinks in a row), low television exposure ( 2 h/d), short afternoon nap ( 30 min/ day), time spent with friends (>1 h/d) and working at least 40 h/week. Results: During a median follow-up of 10.4 years, we observed 774 new cases of major depression among participants initially free of depression. The highest category (8–10 factors) showed a significant inverse association with a 32% relative risk reduction for depression compared to the lowest category (0–3 factors) (multivariable-adjusted hazard ratio: 0.68; 95% CI:0.49-0.95) (p for trend = 0.010). Conclusions: Adopting a healthy-lifestyle was associated with a lower risk of incident depression in the SUN cohort. This index, including ten simple healthy lifestyle habits, may be useful for a more integrative approach to depression prevention. 2024-02-07T11:44:05Z 2024-02-07T11:44:05Z 2019 info:eu-repo/semantics/article https://hdl.handle.net/10171/68878 eng info:eu-repo/grantAgreement/MSC/Redes Temáticas de Investigación Cooperativa en Salud (RETICS)/RD 06/0045/0000/ES/ALIMENTACIÓN SALUDABLE EN LA PREVENCIÓN PRIMARIA DE ENFERMEDADES CRÓNICAS: LA RED PREDIMED info:eu-repo/grantAgreement/MINECO/Proyectos de investigación en salud (AE en Salud)/PI13/00615/ES/ESTILOS DE VIDA Y RIESGO DE DIABETES MELLITUS GESTACIONAL: LA COHORTE SUN info:eu-repo/grantAgreement/MINECO/Proyectos de investigación en salud (AE Salud 2014))/PI14/01668/ES/Dieta y estilos de vida en la prevención de la diabetes mellitus gestacional: un proyecto coordinado de casos y controles y análisis prospectivo de un estudio de cohortes info:eu-repo/semantics/closedAccess application/pdf Elsevier |
| spellingShingle | Materias Investigacion::Ciencias de la Salud::Medicina preventiva Affective disorder Unipolar depression Epidemiology Ruiz-Estigarribia, L. (Liz) Martinez-Gonzalez, M.A. (Miguel Ángel) Diaz-Gutierrez, J. (Jesús) Sanchez-Villegas, A. (Almudena) Lahortiga-Ramos, F. (Francisca) Bes-Rastrollo, M. (Maira) Lifestyles and the risk of depression in the “Seguimiento Universidad de Navarra” cohort |
| title | Lifestyles and the risk of depression in the “Seguimiento Universidad de Navarra” cohort |
| title_full | Lifestyles and the risk of depression in the “Seguimiento Universidad de Navarra” cohort |
| title_fullStr | Lifestyles and the risk of depression in the “Seguimiento Universidad de Navarra” cohort |
| title_full_unstemmed | Lifestyles and the risk of depression in the “Seguimiento Universidad de Navarra” cohort |
| title_short | Lifestyles and the risk of depression in the “Seguimiento Universidad de Navarra” cohort |
| title_sort | lifestyles and the risk of depression in the “seguimiento universidad de navarra” cohort |
| topic | Materias Investigacion::Ciencias de la Salud::Medicina preventiva Affective disorder Unipolar depression Epidemiology |
| url | https://hdl.handle.net/10171/68878 |
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