QobuR – A new in vitro human corneal epithelial model for preclinical drug screening

QobuR – A new in vitro human corneal epithelial model for preclinical drug screening

A new in vitro human corneal epithelial model (QobuR) obtained from normal limbal tissue has been developed to study ocular irritancy of different ophthalmic compounded drugs. Phenotypical characterization and transepithelial electrical resistance (TEER) of QobuR revealed essential similarities com...

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Bibliographic Details
Main Authors: Chacón, M. (Manuel), Vázquez, N. (Natalia), Berisa, S. (Silvia), Persinal, M. (Mairobi), Sanchez, M. (Manuel), Baamonde, B. (Begoña), Alfonso, J.F. (José F.), Fernández-Vega-Cueto, L. (Luis), Merayo-Lloves, J. (Jesús), Meana, A. (Álvaro)
Format: info:eu-repo/semantics/article
Language:eng
Published: Elsevier 2024
Subjects:
Ocular irritancy
Drug absorption
In vitro cornea model
QobuR
TEER measurement
Barrier disruptions
Alternative method
Online Access:https://hdl.handle.net/10171/69070

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