| Summary: | Galactoceles are benign lesions formed at the expense of breast glandular tissue. Its occurrence in boys is exceptional, with
isolated reports in the scientifc literature. We present the case of a 2-year-old boy who debuted with a unilateral breast
enlargement of 18 months of evolution, with no other associated symptoms. Initial hormonal study showed no alterations.
Ultrasonography showed the presence of a homogeneous 5-cm retroareolar cyst. Surgical excision was indicated. During the
procedure, abundant milk drained from the lesion. The histopathological study, supported by GATA-3 immunohistochemical
staining, confrmed the diagnosis of galactocele. The range of possible diferential diagnoses for unilateral or bilateral breast
enlargement in boys is wide and includes neoplastic, vascular, and hormonal etiologies. Galactocele, which is an exceptional
entity in this group, should be considered. Immunohistochemical techniques such as GATA-3, characteristic of the breast
epithelium, can contribute to the diagnosis.
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