Evaluation of Gonadal Alterations in a Population Environmentally Exposed to a Mixture of Endocrine Active Pesticides
Although there are studies that show that some pesticides produce gonadal dysfunction and gonadal cancer in different animals, there are not many studiesregardinghumans. This study determined the prevalence and risk in humans of developing ovarian or testicular dysfunction or cancer in areas with di...
| Main Authors: | , , , , , |
|---|---|
| Format: | info:eu-repo/semantics/article |
| Language: | English |
| Published: |
MDPI
2021
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10835/10041 |
| _version_ | 1789408400608591872 |
|---|---|
| author | Requena-Mullor, Mar Navarro-Mena, Angeles Wei, Ruqiong López-Guarnido, Olga Lozano-Paniagua, David Alarcón Rodríguez, Raquel |
| author_facet | Requena-Mullor, Mar Navarro-Mena, Angeles Wei, Ruqiong López-Guarnido, Olga Lozano-Paniagua, David Alarcón Rodríguez, Raquel |
| author_sort | Requena-Mullor, Mar |
| collection | DSpace |
| description | Although there are studies that show that some pesticides produce gonadal dysfunction and gonadal cancer in different animals, there are not many studiesregardinghumans. This study determined the prevalence and risk in humans of developing ovarian or testicular dysfunction or cancer in areas with distinct exposure to pesticides, which have endocrine disrupting properties. A population-based case-control study was carried out on humans living in ten health districts of Andalusia (Southern Spain) classified as areas of high or low environmental exposure to pesticides according to agronomic criteria. The study population included 5332 cases and 13,606 controls. Data were collected from computerized hospital records between 2000 and 2018.The risk of gonadal dysfunction or cancer was significantly higher in areas with higher use of pesticides in relation to those with lower use. |
| format | info:eu-repo/semantics/article |
| id | oai:repositorio.ual.es:10835-10041 |
| institution | Universidad de Cuenca |
| language | English |
| publishDate | 2021 |
| publisher | MDPI |
| record_format | dspace |
| spelling | oai:repositorio.ual.es:10835-100412023-10-25T12:19:50Z Evaluation of Gonadal Alterations in a Population Environmentally Exposed to a Mixture of Endocrine Active Pesticides Requena-Mullor, Mar Navarro-Mena, Angeles Wei, Ruqiong López-Guarnido, Olga Lozano-Paniagua, David Alarcón Rodríguez, Raquel pesticide endocrine disruption gonadal dysfunction ovarian cancer testicular cancer Although there are studies that show that some pesticides produce gonadal dysfunction and gonadal cancer in different animals, there are not many studiesregardinghumans. This study determined the prevalence and risk in humans of developing ovarian or testicular dysfunction or cancer in areas with distinct exposure to pesticides, which have endocrine disrupting properties. A population-based case-control study was carried out on humans living in ten health districts of Andalusia (Southern Spain) classified as areas of high or low environmental exposure to pesticides according to agronomic criteria. The study population included 5332 cases and 13,606 controls. Data were collected from computerized hospital records between 2000 and 2018.The risk of gonadal dysfunction or cancer was significantly higher in areas with higher use of pesticides in relation to those with lower use. 2021-03-04T08:19:52Z 2021-03-04T08:19:52Z 2021-02-28 info:eu-repo/semantics/article 1660-4601 http://hdl.handle.net/10835/10041 en https://www.mdpi.com/1660-4601/18/5/2355 Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess MDPI |
| spellingShingle | pesticide endocrine disruption gonadal dysfunction ovarian cancer testicular cancer Requena-Mullor, Mar Navarro-Mena, Angeles Wei, Ruqiong López-Guarnido, Olga Lozano-Paniagua, David Alarcón Rodríguez, Raquel Evaluation of Gonadal Alterations in a Population Environmentally Exposed to a Mixture of Endocrine Active Pesticides |
| title | Evaluation of Gonadal Alterations in a Population Environmentally Exposed to a Mixture of Endocrine Active Pesticides |
| title_full | Evaluation of Gonadal Alterations in a Population Environmentally Exposed to a Mixture of Endocrine Active Pesticides |
| title_fullStr | Evaluation of Gonadal Alterations in a Population Environmentally Exposed to a Mixture of Endocrine Active Pesticides |
| title_full_unstemmed | Evaluation of Gonadal Alterations in a Population Environmentally Exposed to a Mixture of Endocrine Active Pesticides |
| title_short | Evaluation of Gonadal Alterations in a Population Environmentally Exposed to a Mixture of Endocrine Active Pesticides |
| title_sort | evaluation of gonadal alterations in a population environmentally exposed to a mixture of endocrine active pesticides |
| topic | pesticide endocrine disruption gonadal dysfunction ovarian cancer testicular cancer |
| url | http://hdl.handle.net/10835/10041 |
| work_keys_str_mv | AT requenamullormar evaluationofgonadalalterationsinapopulationenvironmentallyexposedtoamixtureofendocrineactivepesticides AT navarromenaangeles evaluationofgonadalalterationsinapopulationenvironmentallyexposedtoamixtureofendocrineactivepesticides AT weiruqiong evaluationofgonadalalterationsinapopulationenvironmentallyexposedtoamixtureofendocrineactivepesticides AT lopezguarnidoolga evaluationofgonadalalterationsinapopulationenvironmentallyexposedtoamixtureofendocrineactivepesticides AT lozanopaniaguadavid evaluationofgonadalalterationsinapopulationenvironmentallyexposedtoamixtureofendocrineactivepesticides AT alarconrodriguezraquel evaluationofgonadalalterationsinapopulationenvironmentallyexposedtoamixtureofendocrineactivepesticides |