Fendrix® Vaccine Effectiveness in Healthcare Workers Who Are Non-Responsive to Engerix B® Vaccination
Hepatitis B (HBV) is a pathogen virus with transmission mechanisms that include contact with the infected blood or bodily fluids of the infected organism. Nowadays, healthcare workers are one of the most exposed groups to HBV. Conventionally, completing a vaccine series dosage with Engerix B® lowers...
| Main Authors: | , , , , , |
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| Format: | info:eu-repo/semantics/article |
| Language: | English |
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MDPI
2021
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10835/10484 |
| _version_ | 1789408379387510784 |
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| author | Tejada-Pérez, Juan José Vázquez-Vicente, Juan José Herrera-Burgos, María Renée Martín-Martín, Francisco Gabriel Parrón-Carreño, Tesifón Alarcón Rodríguez, Raquel |
| author_facet | Tejada-Pérez, Juan José Vázquez-Vicente, Juan José Herrera-Burgos, María Renée Martín-Martín, Francisco Gabriel Parrón-Carreño, Tesifón Alarcón Rodríguez, Raquel |
| author_sort | Tejada-Pérez, Juan José |
| collection | DSpace |
| description | Hepatitis B (HBV) is a pathogen virus with transmission mechanisms that include contact with the infected blood or bodily fluids of the infected organism. Nowadays, healthcare workers are one of the most exposed groups to HBV. Conventionally, completing a vaccine series dosage with Engerix B® lowers this risk by providing workers with immunity to the virus. However, through the years, we have encountered nonresponsive health personnel to the Engerix B® vaccine; hence, the Occupational Health Service of Poniente Hospital studied the Fendrix® adjuvanted vaccine as an alternative vaccine to develop immunological responses in healthcare workers who do not respond to vaccination with Engerix B®. In our study, we employed a vaccination schedule with the Fendrix® vaccine, performing serology tests on the cases after the application of each dose. The results obtained showed humoral immunity in 92.3% of the cases, with a remarkable increase in antibody titer after the first doses. These encouraging results support the future inclusion of this vaccine as one possible alternative for the immunization to HBV for healthcare workers nonresponsive to Engerix B® |
| format | info:eu-repo/semantics/article |
| id | oai:repositorio.ual.es:10835-10484 |
| institution | Universidad de Cuenca |
| language | English |
| publishDate | 2021 |
| publisher | MDPI |
| record_format | dspace |
| spelling | oai:repositorio.ual.es:10835-104842023-10-25T12:20:00Z Fendrix® Vaccine Effectiveness in Healthcare Workers Who Are Non-Responsive to Engerix B® Vaccination Tejada-Pérez, Juan José Vázquez-Vicente, Juan José Herrera-Burgos, María Renée Martín-Martín, Francisco Gabriel Parrón-Carreño, Tesifón Alarcón Rodríguez, Raquel Hepatitis B vaccination fendrix healthcare workers occupational health Hepatitis B (HBV) is a pathogen virus with transmission mechanisms that include contact with the infected blood or bodily fluids of the infected organism. Nowadays, healthcare workers are one of the most exposed groups to HBV. Conventionally, completing a vaccine series dosage with Engerix B® lowers this risk by providing workers with immunity to the virus. However, through the years, we have encountered nonresponsive health personnel to the Engerix B® vaccine; hence, the Occupational Health Service of Poniente Hospital studied the Fendrix® adjuvanted vaccine as an alternative vaccine to develop immunological responses in healthcare workers who do not respond to vaccination with Engerix B®. In our study, we employed a vaccination schedule with the Fendrix® vaccine, performing serology tests on the cases after the application of each dose. The results obtained showed humoral immunity in 92.3% of the cases, with a remarkable increase in antibody titer after the first doses. These encouraging results support the future inclusion of this vaccine as one possible alternative for the immunization to HBV for healthcare workers nonresponsive to Engerix B® 2021-04-12T08:05:07Z 2021-04-12T08:05:07Z 2021-03-19 info:eu-repo/semantics/article 2076-393X http://hdl.handle.net/10835/10484 en https://www.mdpi.com/2076-393X/9/3/279 Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess MDPI |
| spellingShingle | Hepatitis B vaccination fendrix healthcare workers occupational health Tejada-Pérez, Juan José Vázquez-Vicente, Juan José Herrera-Burgos, María Renée Martín-Martín, Francisco Gabriel Parrón-Carreño, Tesifón Alarcón Rodríguez, Raquel Fendrix® Vaccine Effectiveness in Healthcare Workers Who Are Non-Responsive to Engerix B® Vaccination |
| title | Fendrix® Vaccine Effectiveness in Healthcare Workers Who Are Non-Responsive to Engerix B® Vaccination |
| title_full | Fendrix® Vaccine Effectiveness in Healthcare Workers Who Are Non-Responsive to Engerix B® Vaccination |
| title_fullStr | Fendrix® Vaccine Effectiveness in Healthcare Workers Who Are Non-Responsive to Engerix B® Vaccination |
| title_full_unstemmed | Fendrix® Vaccine Effectiveness in Healthcare Workers Who Are Non-Responsive to Engerix B® Vaccination |
| title_short | Fendrix® Vaccine Effectiveness in Healthcare Workers Who Are Non-Responsive to Engerix B® Vaccination |
| title_sort | fendrix® vaccine effectiveness in healthcare workers who are non-responsive to engerix b® vaccination |
| topic | Hepatitis B vaccination fendrix healthcare workers occupational health |
| url | http://hdl.handle.net/10835/10484 |
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