Divergent Strategy in Marine Tetracyclic Meroterpenoids Synthesis

The divergent total synthesis strategy can be successfully applied to the preparation of families of natural products using a common late-stage pluripotent intermediate. This approach is a powerful tool in organic synthesis as it offers opportunities for the efficient preparation of structurally rel...

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Bibliographic Details
Main Authors: Rosales Martínez, Antonio, Rodríguez García, Ignacio Manuel, López Martínez, Josefa Leticia
Format: info:eu-repo/semantics/article
Language:English
Published: MDPI 2021
Subjects:
Online Access:http://hdl.handle.net/10835/11927
https://doi.org/10.3390/md19050273
Description
Summary:The divergent total synthesis strategy can be successfully applied to the preparation of families of natural products using a common late-stage pluripotent intermediate. This approach is a powerful tool in organic synthesis as it offers opportunities for the efficient preparation of structurally related compounds. This article reviews the synthesis of the marine natural product aureol, as well as its use as a common intermediate in the divergent synthesis of other marine natural and non-natural tetracyclic meroterpenoids